Systematic Understanding of the Mechanism of Salvianolic Acid A via Computational Target Fishing

Salvianolic acid A (SAA) is one of the most abundant water-soluble and potent anti-oxidative compounds isolated from Danshen, a traditional Chinese medicine. A systematic overview of its mechanism of action is yet to be performed. In the present study, the druggability of SAA was measured using the...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2017-04, Vol.22 (4), p.644
Hauptverfasser:	Chen, Shao-Jun, Cui, Ming-Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Bioavailability Blood-brain barrier Caffeic Acids - chemistry Caffeic Acids - pharmacology Cancer Chinese medicine Computer applications Cystic fibrosis Fishing Genes Herbal medicine Investigations Lactates - chemistry Lactates - pharmacology Localization Metabolism Models, Biological Models, Molecular Network analysis Permeability Pharmacology Physiology Protein Binding Proteins Salvia miltiorrhiza - chemistry Signal Transduction - drug effects Structure-Activity Relationship
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