The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development

Tooth morphogenesis is initiated by reciprocal interactions between the ectoderm and neural crest–derived mesenchyme. During tooth development, tooth cusps are regulated by precise control of proliferation of cell clusters, termed enamel knots, that are present among dental epithelial cells. The int...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2018-09, Vol.293 (38), p.14572-14584
Hauptverfasser:	Han, Xue, Yoshizaki, Keigo, Miyazaki, Kanako, Arai, Chieko, Funada, Keita, Yuta, Tomomi, Tian, Tian, Chiba, Yuta, Saito, Kan, Iwamoto, Tsutomu, Yamada, Aya, Takahashi, Ichiro, Fukumoto, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cell differentiation cell proliferation Cell Proliferation - physiology Cyclin-Dependent Kinase Inhibitor p21 - genetics Cyclin-Dependent Kinase Inhibitor p21 - metabolism Dental Enamel - cytology Dental Enamel - metabolism dental growth development Developmental Biology Ectodysplasins - metabolism Edar Receptor Epithelial Cells - metabolism Female Genes, Homeobox Homeodomain Proteins - genetics Homeodomain Proteins - physiology Mice Mice, Knockout Morphogenesis Nkx2–3 odontogenesis Odontogenesis - genetics Odontogenesis - physiology Organ Culture Techniques Pregnancy Promoter Regions, Genetic Signal Transduction - physiology SOXB1 Transcription Factors - metabolism tissue-specific transcription factor tooth Transcription Factors - genetics Transcription Factors - physiology transcription regulation Transcription, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!