The conditioned medium of human mesenchymal stromal cells reduces irradiation-induced damage in cardiac fibroblast cells

Recently, multipotent mesenchymal stromal cell (MSC) treatment has attracted special attention as a new alternative strategy for stimulating regeneration. Irradiation myocardial fibrosis (IMF) is a major complication associated with total body irradiation for hematopoietic stem cell transplantation,...

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Veröffentlicht in:	Journal of radiation research 2018-09, Vol.59 (5), p.555-564
Hauptverfasser:	Chen, Zhu-Yue, Hu, Ying-Ying, Hu, Xiao-Fan, Cheng, Long-Xian
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Cell Proliferation - drug effects Cell Survival Collagen Type I - metabolism Collagen Type XI - metabolism Culture Media, Conditioned - chemistry Fibroblasts - cytology Fibroblasts - radiation effects Humans Inflammation Lipid Peroxidation Mesenchymal Stem Cells - cytology Myocardium - cytology NF-kappa B - metabolism Oxidative Stress Radiation Injuries Regular Paper RNA, Messenger - metabolism Signal Transduction Transforming Growth Factor beta1 - metabolism Umbilical Cord - cytology
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