Micro-RNAs involved in cellular proliferation have altered expression profiles in granulosa of young women with diminished ovarian reserve

Purpose The study aims to determine differences in micro-RNA (miRNA) expression in granulosa (GC) and cumulus cells (CC) between young women with diminished ovarian reserve (DOR) or normal ovarian reserve (NOR). Secondary objective was to identify downstream signaling pathways that could ultimately...

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Veröffentlicht in:	Journal of assisted reproduction and genetics 2018-10, Vol.35 (10), p.1777-1786
Hauptverfasser:	Woo, Irene, Christenson, Lane K., Gunewardena, Sumedha, Ingles, Sue Ann, Thomas, Semara, Ahmady, Ali, Chung, Karine, Bendikson, Kristin, Paulson, Richard, McGinnis, Lynda K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell growth Cell Proliferation Cell survival Cells, Cultured Cumulus Cells - metabolism Cumulus Cells - pathology Female Gene Expression Profiling Granulosa Cells - metabolism Granulosa Cells - pathology Gynecology Human Genetics Humans MAP kinase Medicine Medicine & Public Health MicroRNAs - genetics miRNA Oocytes Ovarian Diseases - metabolism Ovarian Diseases - pathology Ovarian Reserve Prospective Studies Reproductive Medicine Reproductive Physiology and Disease Wnt protein
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