Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma

Classical Hodgkin lymphoma (cHL) is an unusual B-cell-derived malignancy in which rare malignant Hodgkin and Reed-Sternberg (HRS) cells are surrounded by an extensive but ineffective inflammatory/immune cell infiltrate. This striking feature suggests that malignant HRS cells escape immunosurveillanc...

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Veröffentlicht in:	Hematology 2017-12, Vol.2017 (1), p.310-316
Hauptverfasser:	Liu, W Robert, Shipp, Margaret A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes, Human, Pair 9 - genetics Chromosomes, Human, Pair 9 - immunology Hodgkin Disease - genetics Hodgkin Disease - immunology Hodgkin Disease - pathology Hodgkin Lymphoma: New Insights and New Approaches Humans Neoplasm Proteins - genetics Neoplasm Proteins - immunology Signal Transduction - genetics Tumor Escape - drug effects Tumor Escape - genetics Tumor Microenvironment - genetics Tumor Microenvironment - immunology
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