Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization

Mucins are essential for airway defense against bacteria. We hypothesized that abnormal secreted airway mucin levels would be associated with bacterial colonization in patients with severe chronic obstructive pulmonary disease (COPD) Objectives: To investigate the relationship between mucin levels a...

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Veröffentlicht in:	Annals of the American Thoracic Society 2016-05, Vol.13 (5), p.636-642
Hauptverfasser:	Sibila, Oriol, Garcia-Bellmunt, Laia, Giner, Jordi, Rodrigo-Troyano, Ana, Suarez-Cuartin, Guillermo, Torrego, Alfons, Castillo, Diego, Solanes, Ingrid, Mateus, Eder F, Vidal, Silvia, Sanchez-Reus, Ferran, Sala, Ernest, Cosio, Borja G, Restrepo, Marcos I, Anzueto, Antonio, Chalmers, James D, Plaza, Vicente
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers - analysis Bronchoalveolar Lavage Fluid - microbiology Bronchoscopy Cross-Sectional Studies Female Humans Interleukin-6 - analysis Linear Models Lung - microbiology Lung - physiopathology Male Middle Aged Mucin-2 - analysis Original Research Prospective Studies Pulmonary Disease, Chronic Obstructive - microbiology Pulmonary Disease, Chronic Obstructive - physiopathology Spain Sputum - microbiology Vital Capacity
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