Hypoxia Imaging and Biological Evaluation of the Radiosensitizing Effect of Oleanolic Acid

Background and Purpose. The aim of this study was to evaluate the radiosensitizing effect of oleanolic acid (OA) on C6 rat glioma and the changes in tumor biology during radiosensitization therapy on 18F-fluoromisonidazole (18F-FMISO) positron emission tomography/computed tomography (PET/CT). Method...

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Veröffentlicht in:	BioMed research international 2018-01, Vol.2018 (2018), p.1-9
Hauptverfasser:	Xiao, Liang, Xue, Yangyang, Yu, Wenjing, Zhang, Yu, Wang, Hui, Xu, Huiqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Archives & records Bioindicators Biological products Biology Biomarkers Brain Neoplasms - therapy Brain tumors Breast cancer Cell Hypoxia Computed tomography Evaluation Fluorine isotopes Fluorodeoxyglucose F18 Glioma Glioma - therapy Gliomas Glucose transporter Growth rate Herbal medicine Hypoxia Hypoxia-inducible factors Image processing Immunohistochemistry Irradiation Medical prognosis Medical research Muscles Oleanolic acid Oleanolic Acid - pharmacology p53 Protein PET imaging Physiology Positron emission Positron emission tomography Positron Emission Tomography Computed Tomography R&D Radiation Radiation-Sensitizing Agents - pharmacology Radiopharmaceuticals Radiosensitization Radiotherapy Rats Research & development Rodents Survival Therapy Tumor Cells, Cultured Tumor proteins Tumor suppressor genes Tumors
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