Calprotectin protects against experimental colonic inflammation in mice

Background and Purpose Calprotectin is a heterodimer composed of two myeloid‐related proteins, S100A8 and S100A9, that is abundant in neutrophils and monocytes/macrophages. Faecal levels of calprotectin are used routinely to monitor inflammatory bowel disease activity. Experimental Approach We aimed...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 2018-10, Vol.175 (19), p.3797-3812
Hauptverfasser:	Aranda, Carlos J, Ocón, Borja, Arredondo‐Amador, María, Suárez, María Dolores, Zarzuelo, Antonio, Chazin, Walter J, Martínez‐Augustin, Olga, Sánchez de Medina, Fermín
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Rectal Advanced glycosylation end products Animals Body weight Body weight loss Cells, Cultured Chemokines Colitis Colitis - chemically induced Colitis - drug therapy Colitis - pathology Colitis - prevention & control Colon Dextran Dextran sulfate Dextran Sulfate - antagonists & inhibitors Disease Models, Animal Epithelial cells Epithelium Female Glycosylation Inflammation - chemically induced Inflammation - drug therapy Inflammation - pathology Inflammation - prevention & control Inflammatory bowel disease Inflammatory bowel diseases Injection Intestine Leukocyte L1 Antigen Complex - administration & dosage Leukocyte L1 Antigen Complex - pharmacology Leukocytes (neutrophilic) Lymph nodes Macrophages Mice Mice, Inbred C57BL Microbiota Monocyte chemoattractant protein 1 Monocytes NF-κB protein Peroxidase Proteins Research Paper Research Papers Rodents Sodium Spleen Toll-like receptors Tumor necrosis factor-α Weight loss
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!