MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS

Immunoglobulin G (IgG) N - glycosylation is crucial for its effector functions. It is a complex trait, and large sample sets are needed to discover multiple genetic factors that underlie it. While in humans such high-throughput studies of IgG N-glycans became usual, only one has been carried out in...

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Veröffentlicht in:	Scientific reports 2018-09, Vol.8 (1), p.13688-9, Article 13688
Hauptverfasser:	Zaytseva, Olga O., Jansen, Bas C., Hanić, Maja, Mrčela, Mia, Razdorov, Genadij, Stojković, Ranko, Erhardt, Julija, Brizić, Ilija, Jonjić, Stipan, Pezer, Marija, Lauc, Gordan
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/296 631/92/1268 64/60 82/83 Biochemistry Biological variation Chromatography Data processing Genetic factors Glycoproteins Glycosylation Humanities and Social Sciences Immunoglobulin G Immunoglobulins Inbreeding Laboratories Liquid chromatography multidisciplinary N-glycans Peptides Polysaccharides Proteins Science Science (multidisciplinary) Scientific imaging Spectrometry
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