Inhibition of RKIP aggravates thioacetamide-induced acute liver failure in mice

Accumulating evidence has indicated that Raf kinase inhibitor protein (RKIP) is involved in several intracellular signaling pathways; its abnormal expression is associated with tumor progression and metastasis in several human neoplasms. However, the role of RKIP in acute liver injury has remained e...

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Veröffentlicht in:	Experimental and therapeutic medicine 2018-10, Vol.16 (4), p.2992-2998
Hauptverfasser:	Lin, Xing, Wei, Jinbin, Nie, Jinlan, Bai, Facheng, Zhu, Xunshuai, Zhuo, Lang, Lu, Zhongpeng, Huang, Quanfang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Care and treatment Cytokines Inflammation Inflammatory diseases Kinase inhibitors Kinases Liver Liver failure Medical research Membranes Oxidative stress Phosphorylation Prevention Proteins Reactive oxygen species Rodents Signal transduction Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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