Ceftaroline Resistance by Clone-Specific Polymorphism in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus

A total of 281 nonduplicated blood isolates were collected from January to May 2017 from eight hospitals in South Korea to investigate the epidemiological traits of ceftaroline resistance in methicillin-resistant (MRSA). Cefoxitin-disk diffusion tests and the gene PCR revealed that 56.6% (159/281) o...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-09, Vol.62 (9)
Hauptverfasser:	Lee, Hyukmin, Yoon, Eun-Jeong, Kim, Dokyun, Kim, Jung Wook, Lee, Kwang-Jun, Kim, Hyun Soo, Kim, Young Ree, Shin, Jong Hee, Shin, Jeong Hwan, Shin, Kyeong Seob, Kim, Young Ah, Uh, Young, Jeong, Seok Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology Bacterial Proteins Bacterial Proteins - genetics Cefoxitin - pharmacology Ceftaroline Cephalosporins Cephalosporins - pharmacology Humans Mechanisms of Resistance Methicillin-Resistant Staphylococcus aureus Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - genetics Microbial Sensitivity Tests - methods Penicillin-Binding Proteins Penicillin-Binding Proteins - genetics Polymorphism, Genetic Polymorphism, Genetic - genetics Republic of Korea Staphylococcal Infections Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology
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