Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis

The UKMYC5 plate is a 96-well microtiter plate designed by the CRyPTIC Consortium (Comprehensive Resistance Prediction for Tuberculosis: an International Consortium) to enable the measurement of MICs of 14 different antituberculosis (anti-TB) compounds for >30,000 clinical isolates. Unlike the MY...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-09, Vol.62 (9)
Hauptverfasser:	Rancoita, Paola M V, Cugnata, Federica, Gibertoni Cruz, Ana Luíza, Borroni, Emanuele, Hoosdally, Sarah J, Walker, Timothy M, Grazian, Clara, Davies, Timothy J, Peto, Timothy E A, Crook, Derrick W, Fowler, Philip W, Cirillo, Daniela M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular Agents Antitubercular Agents - pharmacology Clofazimine - pharmacology Diarylquinolines Diarylquinolines - pharmacology Drug Resistance, Multiple, Bacterial - drug effects Humans Linezolid - pharmacology Microbial Sensitivity Tests - methods Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Nitroimidazoles Nitroimidazoles - pharmacology Oxazoles Oxazoles - pharmacology Reproducibility of Results Susceptibility Tuberculosis Tuberculosis - drug therapy Tuberculosis, Multidrug-Resistant Tuberculosis, Multidrug-Resistant - drug therapy
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