Sanger and Next Generation Sequencing Approaches to Evaluate HIV-1 Virus in Blood Compartments

The implementation of antiretroviral treatment combined with the monitoring of drug resistance mutations improves the quality of life of HIV-1 positive patients. The drug resistance mutation patterns and viral genotypes are currently analyzed by DNA sequencing of the virus in the plasma of patients....

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Veröffentlicht in:	International journal of environmental research and public health 2018-08, Vol.15 (8), p.1697
Hauptverfasser:	Arias, Andrea, López, Pablo, Sánchez, Raphael, Yamamura, Yasuhiro, Rivera-Amill, Vanessa
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Blood plasma Brief Report CD4 antigen CD45RA antigen Compartments Data processing Deoxyribonucleic acid Disease control Disease resistance DNA DNA sequencing Drug resistance Drug Resistance, Viral - genetics Genotypes High-Throughput Nucleotide Sequencing HIV HIV Infections - blood HIV Infections - virology HIV-1 - genetics Human immunodeficiency virus Humans Immunological memory Leukocytes (mononuclear) Leukocytes, Mononuclear - virology Lymphocytes Lymphocytes T Male Memory cells Mutation Patients Peripheral blood mononuclear cells Polymerase chain reaction Quality of life RNA-directed DNA polymerase Sequence Analysis, DNA Software development Viruses
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