Somatic TP53 Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors12

BACKGROUND: Diffuse anaplastic Wilms tumor (DAWT) is a rare, high-risk subtype that is often missed on diagnostic needle biopsy. Somatic mutations in TP53 are associated with the development of anaplasia and with poorer survival, particularly in advanced-stage disease. Early identification of DAWT h...

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Veröffentlicht in:	Translational oncology 2018-08, Vol.11 (6), p.1301-1306
Hauptverfasser:	Treger, Taryn D., Chagtai, Tasnim, Butcher, Robert, Cresswell, George D., Al-Saadi, Reem, Brok, Jesper, Williams, Richard D., Roberts, Chrissy, Luscombe, Nicholas M., Pritchard Jones, Kathy, Mifsud, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Original article
Online-Zugang:	Volltext
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