Simplification of complex DNA profiles using front end cell separation and probabilistic modeling

•A series of dried blood mixtures containing as many as five individuals were analyzed.•Contributor cell populations were labeled with antibody probes and separated into two fractions.•DNA profiles from each fraction could be interpreted manually or using probabilistic modeling.•This approach can in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Forensic science international : genetics 2018-09, Vol.36, p.205-212
Hauptverfasser:	Stokes, Nancy A., Stanciu, Cristina E., Brocato, Emily R., Ehrhardt, Christopher J., Greenspoon, Susan A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Blood Chemical Analysis Cell Separation DNA - analysis DNA Fingerprinting - methods DNA mixtures Flow Cytometry Fluorescence Humans Microsatellite Repeats Models, Statistical Molecular Probes Probabilistic modeling Real-Time Polymerase Chain Reaction TrueAllele
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!