Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania

The contribution of hepcidin as a regulator of iron metabolism & erythropoiesis on the severity of anemia in sickle cell disease (SCD) remains poorly characterized, especially in Sub-Saharan African populations. The aims of the study were to determine if hepcidin is associated with severity of s...

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Veröffentlicht in:	EBioMedicine 2018-08, Vol.34, p.158-164
Hauptverfasser:	Lee, Nathaniel, Makani, Julie, Tluway, Furahini, Makubi, Abel, Armitage, Andrew E., Pasricha, Sant-Rayn, Drakesmith, Hal, Prentice, Andrew M., Cox, Sharon E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anemia, Sickle Cell - blood Child Child, Preschool Female Hemoglobins - analysis Hepcidin Hepcidins - blood Humans Iron metabolism Male Nutrition Research Paper Severity of Illness Index Sickle cell anemia Sickle cell disease Sub-Saharan Africa Tanzania
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