Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms
Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI symptom...
Gespeichert in:
| Veröffentlicht in: | Pakistan Journal of Medical Sciences 2018-08, Vol.34 (4), p.1004-1009 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1009 |
|---|---|
| container_issue | 4 |
| container_start_page | 1004 |
| container_title | Pakistan Journal of Medical Sciences |
| container_volume | 34 |
| creator | Aslam, Faisal Khalid, Abdullah Bin Siddiqui, Faraz Jadoon, Yamna |
| description | Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI symptoms with abnormal endoscopic findings and to cut off the burden and cost of unnecessary endoscopies.
This is cross sectional study of anemic patient who underwent upper and lower GI endoscopies in Aga Khan University Hospital, Karachi between July-December 2016.
Total 243 patients were identified after excluding ineligible patients. The mean age of subjects was 31.9 ± 6.1 years with a slight over-representation of females (57.4%). 149 (61.31%) patients underwent only upper GI endoscopic evaluation, and 83 (34.15%) patients on whom bi-directional endoscopy was performed (upper and lower). The remaining 11 (4.52%) patients underwent colonoscopy only. 16 (6.6%) subjects had negative findings on evaluation, while gastritis and serious findings were observed in 175 (72.0%) and 52 (21.4%) patients respectively. We found that patients with alarm features such as dysphagia (aOR: 2.07, 95%CI: 0.12-34.1), altered bowel habits (aOR: 1.64, 95%CI: 0.44-6.09) and weight loss (aOR: 1.25 95%CI: 0.54-2.85) demonstrated higher odds of serious findings on endoscopic evaluation as compared to the reference category, however they were not independently associated.
Most of our patients had non-malignant pathologies, while alarm features were not found to be useful predictors of serious findings. |
| doi_str_mv | 10.12669/pjms.344.14391 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115569</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A557432681</galeid><sourcerecordid>A557432681</sourcerecordid><originalsourceid>FETCH-LOGICAL-c473t-d9ec790c8a863f20606d490e360f043cb16d38f272a93efcedef2c7a6c7571fc3</originalsourceid><addsrcrecordid>eNptks9rFDEUxwdRbG179iYBoXiZbX5NsnMRStFaKOhBobeQTV52sswkYzKj7H_f7LbWrkgOL7x83kvyfd-qekvwglAh2otxM-QF43xBOGvJi-qYiCWpJWnuXu73tMaU3x1Vb3LeYMwFb-jr6ohh0mIp8XHVfUtgvZliyig6lCH5OGfkfLA-rEsuoJWvrU9gJh-D7hEEG7OJ4xb5gLZxDms06slDmDL67acO6QCD1yVYdH2D8nYYpzjk0-qV032Gs8d4Uv34_On71Zf69uv1zdXlbW24ZFNtWzCyxWapl4I5igUWlrcYmMAOc2ZWRFi2dFRS3TJwBiw4aqQWRjaSOMNOqo8Pfcd5NYA15V1J92pMftBpq6L26vAk-E6t4y8lCGka0ZYGHx4bpPhzhjypwWcDfV_-VaRRlGBCJecSF_T9P-gmzqmItKOoaKggrPlLrXUPygcXy71m11RdNo3kjJaRFWrxH6osW9Q0MYDzJX9QcP6soAPdT12O_bwbUz4ELx5Ak2LOCdyTGASrvYvUzkWquEjtXVQq3j3X8In_Yxt2D0-cw6I</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2126526135</pqid></control><display><type>article</type><title>Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Aslam, Faisal ; Khalid, Abdullah Bin ; Siddiqui, Faraz ; Jadoon, Yamna</creator><creatorcontrib>Aslam, Faisal ; Khalid, Abdullah Bin ; Siddiqui, Faraz ; Jadoon, Yamna</creatorcontrib><description>Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI symptoms with abnormal endoscopic findings and to cut off the burden and cost of unnecessary endoscopies.
This is cross sectional study of anemic patient who underwent upper and lower GI endoscopies in Aga Khan University Hospital, Karachi between July-December 2016.
Total 243 patients were identified after excluding ineligible patients. The mean age of subjects was 31.9 ± 6.1 years with a slight over-representation of females (57.4%). 149 (61.31%) patients underwent only upper GI endoscopic evaluation, and 83 (34.15%) patients on whom bi-directional endoscopy was performed (upper and lower). The remaining 11 (4.52%) patients underwent colonoscopy only. 16 (6.6%) subjects had negative findings on evaluation, while gastritis and serious findings were observed in 175 (72.0%) and 52 (21.4%) patients respectively. We found that patients with alarm features such as dysphagia (aOR: 2.07, 95%CI: 0.12-34.1), altered bowel habits (aOR: 1.64, 95%CI: 0.44-6.09) and weight loss (aOR: 1.25 95%CI: 0.54-2.85) demonstrated higher odds of serious findings on endoscopic evaluation as compared to the reference category, however they were not independently associated.
Most of our patients had non-malignant pathologies, while alarm features were not found to be useful predictors of serious findings.</description><identifier>ISSN: 1682-024X</identifier><identifier>ISSN: 1681-715X</identifier><identifier>EISSN: 1681-715X</identifier><identifier>DOI: 10.12669/pjms.344.14391</identifier><identifier>PMID: 30190770</identifier><language>eng</language><publisher>Pakistan: Knowledge Bylanes</publisher><subject>Anemia ; Celiac disease ; Colonoscopy ; Diabetes ; Dysphagia ; Endoscopy ; Esophagus ; Gastric cancer ; Gastroenterology ; Health risk assessment ; Inflammatory bowel disease ; Iron ; Kidney diseases ; Medical research ; Original ; Primary care ; Studies ; Systematic review ; Ulcers ; Varicose veins</subject><ispartof>Pakistan Journal of Medical Sciences, 2018-08, Vol.34 (4), p.1004-1009</ispartof><rights>COPYRIGHT 2018 Knowledge Bylanes</rights><rights>Copyright AsiaNet Pakistan (Pvt) Ltd. Aug 31, 2018</rights><rights>Copyright: © Pakistan Journal of Medical Sciences 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115569/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115569/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30190770$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aslam, Faisal</creatorcontrib><creatorcontrib>Khalid, Abdullah Bin</creatorcontrib><creatorcontrib>Siddiqui, Faraz</creatorcontrib><creatorcontrib>Jadoon, Yamna</creatorcontrib><title>Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms</title><title>Pakistan Journal of Medical Sciences</title><addtitle>Pak J Med Sci</addtitle><description>Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI symptoms with abnormal endoscopic findings and to cut off the burden and cost of unnecessary endoscopies.
This is cross sectional study of anemic patient who underwent upper and lower GI endoscopies in Aga Khan University Hospital, Karachi between July-December 2016.
Total 243 patients were identified after excluding ineligible patients. The mean age of subjects was 31.9 ± 6.1 years with a slight over-representation of females (57.4%). 149 (61.31%) patients underwent only upper GI endoscopic evaluation, and 83 (34.15%) patients on whom bi-directional endoscopy was performed (upper and lower). The remaining 11 (4.52%) patients underwent colonoscopy only. 16 (6.6%) subjects had negative findings on evaluation, while gastritis and serious findings were observed in 175 (72.0%) and 52 (21.4%) patients respectively. We found that patients with alarm features such as dysphagia (aOR: 2.07, 95%CI: 0.12-34.1), altered bowel habits (aOR: 1.64, 95%CI: 0.44-6.09) and weight loss (aOR: 1.25 95%CI: 0.54-2.85) demonstrated higher odds of serious findings on endoscopic evaluation as compared to the reference category, however they were not independently associated.
Most of our patients had non-malignant pathologies, while alarm features were not found to be useful predictors of serious findings.</description><subject>Anemia</subject><subject>Celiac disease</subject><subject>Colonoscopy</subject><subject>Diabetes</subject><subject>Dysphagia</subject><subject>Endoscopy</subject><subject>Esophagus</subject><subject>Gastric cancer</subject><subject>Gastroenterology</subject><subject>Health risk assessment</subject><subject>Inflammatory bowel disease</subject><subject>Iron</subject><subject>Kidney diseases</subject><subject>Medical research</subject><subject>Original</subject><subject>Primary care</subject><subject>Studies</subject><subject>Systematic review</subject><subject>Ulcers</subject><subject>Varicose veins</subject><issn>1682-024X</issn><issn>1681-715X</issn><issn>1681-715X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNptks9rFDEUxwdRbG179iYBoXiZbX5NsnMRStFaKOhBobeQTV52sswkYzKj7H_f7LbWrkgOL7x83kvyfd-qekvwglAh2otxM-QF43xBOGvJi-qYiCWpJWnuXu73tMaU3x1Vb3LeYMwFb-jr6ohh0mIp8XHVfUtgvZliyig6lCH5OGfkfLA-rEsuoJWvrU9gJh-D7hEEG7OJ4xb5gLZxDms06slDmDL67acO6QCD1yVYdH2D8nYYpzjk0-qV032Gs8d4Uv34_On71Zf69uv1zdXlbW24ZFNtWzCyxWapl4I5igUWlrcYmMAOc2ZWRFi2dFRS3TJwBiw4aqQWRjaSOMNOqo8Pfcd5NYA15V1J92pMftBpq6L26vAk-E6t4y8lCGka0ZYGHx4bpPhzhjypwWcDfV_-VaRRlGBCJecSF_T9P-gmzqmItKOoaKggrPlLrXUPygcXy71m11RdNo3kjJaRFWrxH6osW9Q0MYDzJX9QcP6soAPdT12O_bwbUz4ELx5Ak2LOCdyTGASrvYvUzkWquEjtXVQq3j3X8In_Yxt2D0-cw6I</recordid><startdate>20180831</startdate><enddate>20180831</enddate><creator>Aslam, Faisal</creator><creator>Khalid, Abdullah Bin</creator><creator>Siddiqui, Faraz</creator><creator>Jadoon, Yamna</creator><general>Knowledge Bylanes</general><general>AsiaNet Pakistan (Pvt) Ltd</general><general>Professional Medical Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180831</creationdate><title>Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms</title><author>Aslam, Faisal ; Khalid, Abdullah Bin ; Siddiqui, Faraz ; Jadoon, Yamna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-d9ec790c8a863f20606d490e360f043cb16d38f272a93efcedef2c7a6c7571fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Anemia</topic><topic>Celiac disease</topic><topic>Colonoscopy</topic><topic>Diabetes</topic><topic>Dysphagia</topic><topic>Endoscopy</topic><topic>Esophagus</topic><topic>Gastric cancer</topic><topic>Gastroenterology</topic><topic>Health risk assessment</topic><topic>Inflammatory bowel disease</topic><topic>Iron</topic><topic>Kidney diseases</topic><topic>Medical research</topic><topic>Original</topic><topic>Primary care</topic><topic>Studies</topic><topic>Systematic review</topic><topic>Ulcers</topic><topic>Varicose veins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aslam, Faisal</creatorcontrib><creatorcontrib>Khalid, Abdullah Bin</creatorcontrib><creatorcontrib>Siddiqui, Faraz</creatorcontrib><creatorcontrib>Jadoon, Yamna</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Pakistan Journal of Medical Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aslam, Faisal</au><au>Khalid, Abdullah Bin</au><au>Siddiqui, Faraz</au><au>Jadoon, Yamna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms</atitle><jtitle>Pakistan Journal of Medical Sciences</jtitle><addtitle>Pak J Med Sci</addtitle><date>2018-08-31</date><risdate>2018</risdate><volume>34</volume><issue>4</issue><spage>1004</spage><epage>1009</epage><pages>1004-1009</pages><issn>1682-024X</issn><issn>1681-715X</issn><eissn>1681-715X</eissn><abstract>Iron deficiency anemia (IDA) has been cited as the most common cause of anemia globally. Gastrointestinal (GI) lesions are amongst the common cause of IDA. Endoscopic evaluation is the most effective way to investigate the IDA. The aim of this study was to show the association of alarming GI symptoms with abnormal endoscopic findings and to cut off the burden and cost of unnecessary endoscopies.
This is cross sectional study of anemic patient who underwent upper and lower GI endoscopies in Aga Khan University Hospital, Karachi between July-December 2016.
Total 243 patients were identified after excluding ineligible patients. The mean age of subjects was 31.9 ± 6.1 years with a slight over-representation of females (57.4%). 149 (61.31%) patients underwent only upper GI endoscopic evaluation, and 83 (34.15%) patients on whom bi-directional endoscopy was performed (upper and lower). The remaining 11 (4.52%) patients underwent colonoscopy only. 16 (6.6%) subjects had negative findings on evaluation, while gastritis and serious findings were observed in 175 (72.0%) and 52 (21.4%) patients respectively. We found that patients with alarm features such as dysphagia (aOR: 2.07, 95%CI: 0.12-34.1), altered bowel habits (aOR: 1.64, 95%CI: 0.44-6.09) and weight loss (aOR: 1.25 95%CI: 0.54-2.85) demonstrated higher odds of serious findings on endoscopic evaluation as compared to the reference category, however they were not independently associated.
Most of our patients had non-malignant pathologies, while alarm features were not found to be useful predictors of serious findings.</abstract><cop>Pakistan</cop><pub>Knowledge Bylanes</pub><pmid>30190770</pmid><doi>10.12669/pjms.344.14391</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1682-024X |
| ispartof | Pakistan Journal of Medical Sciences, 2018-08, Vol.34 (4), p.1004-1009 |
| issn | 1682-024X 1681-715X 1681-715X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115569 |
| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; PubMed Central; Alma/SFX Local Collection |
| subjects | Anemia Celiac disease Colonoscopy Diabetes Dysphagia Endoscopy Esophagus Gastric cancer Gastroenterology Health risk assessment Inflammatory bowel disease Iron Kidney diseases Medical research Original Primary care Studies Systematic review Ulcers Varicose veins |
| title | Predictors of serious findings on bi-directional endoscopy in young patients with anemia and GI symptoms |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T12%3A35%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Predictors%20of%20serious%20findings%20on%20bi-directional%20endoscopy%20in%20young%20patients%20with%20anemia%20and%20GI%20symptoms&rft.jtitle=Pakistan%20Journal%20of%20Medical%20Sciences&rft.au=Aslam,%20Faisal&rft.date=2018-08-31&rft.volume=34&rft.issue=4&rft.spage=1004&rft.epage=1009&rft.pages=1004-1009&rft.issn=1682-024X&rft.eissn=1681-715X&rft_id=info:doi/10.12669/pjms.344.14391&rft_dat=%3Cgale_pubme%3EA557432681%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2126526135&rft_id=info:pmid/30190770&rft_galeid=A557432681&rfr_iscdi=true |