Cell type-dependent effects of ellagic acid on cellular metabolism

[Display omitted] •Ellagic acid impacts mitochondrial function at therapeutically relevant doses.•Ellagic acid has complex cell type-dependent effects on cellular respiration.•Ellagic acid is not a potent inducer of cell death signaling. Ellagic acid is a botanical polyphenol which has been shown to...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2018-10, Vol.106, p.411-418
Hauptverfasser:	Boehning, Alexandra L., Essien, Safia A., Underwood, Erica L., Dash, Pramod K., Boehning, Darren
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects Cancer Caspase 3 - metabolism Caspase 6 - metabolism Dose-Response Relationship, Drug Ellagic acid Ellagic Acid - pharmacology Energy Metabolism - drug effects Glycolysis HEK293 Cells HeLa Cells Hep G2 Cells Humans MCF-7 Cells Membrane Potential, Mitochondrial - drug effects Mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitochondria - pathology Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - pathology Respiration Time Factors
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