Receptor CD36 links a risk-associated allele to obesity and metabolic disorders

Mice harboring a particular allele of the human brain-derived neurotropic factor (BDNFM/M mice) develop extreme obesity and insulin resistance when fed a high-fat diet. The underlying mechanisms of this genetic risk factor for obesity are unclear. In the current issue of JBC, Yang et al. report that...

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Veröffentlicht in:	The Journal of biological chemistry 2018-08, Vol.293 (34), p.13349-13350
Hauptverfasser:	Liu, Min, Tso, Patrick, Woods, Stephen C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - metabolism CD36 Antigens - metabolism Editors' Picks Highlights Humans Metabolic Diseases - physiopathology Mice Mutation Obesity - physiopathology
Online-Zugang:	Volltext
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