Geriatric nutritional risk index predicts surgical site infection after pancreaticoduodenectomy
Surgical site infections (SSIs) are a well-known potential complication of surgery. They are assocaited with preoperative malnutrition and lead to increased medical costs and longer hospital stays. Therefore, surgeons should appropriately identify patients who are at a high risk. The geriatric nutri...
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| Veröffentlicht in: | Molecular and clinical oncology 2018-09, Vol.9 (3), p.274-278 |
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| creator | Funamizu, Naotake Nakabayashi, Yukio Iida, Tomonori Kurihara, Kazunao |
| description | Surgical site infections (SSIs) are a well-known potential complication of surgery. They are assocaited with preoperative malnutrition and lead to increased medical costs and longer hospital stays. Therefore, surgeons should appropriately identify patients who are at a high risk. The geriatric nutritional risk index (GNRI) is a tool, increasingly utilized to assess the degree of malnutrition, particularly in elderly patients. Therefore, the present study attempted to validate whether GNRI could predict the risk of SSI in patients following pancreaticoduodenectomy (PD). A cohort study was retrospectively conducted on 106 patients in the Department of Digestive Surgery, Kawaguchi Municipal Medical Center, Japan from January 2007 to December 2017. All patients were subjected to nutritional screening using GNRI and followed up for the occurrence of postoperative complications, including SSI post PD. Additionally, risk factors for developing SSI, and the patient's height, body mass index and preoperative laboratory values were documented. Patients were divided into SSI (n=15) and non-SSI (n=91) groups with a determined incidence of 14.2% (15/106) for SSI. The results revealed that the SSI group had GNRI values that were significantly reduced compared with the non-SSI group (P |
| doi_str_mv | 10.3892/mco.2018.1671 |
| format | Article |
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They are assocaited with preoperative malnutrition and lead to increased medical costs and longer hospital stays. Therefore, surgeons should appropriately identify patients who are at a high risk. The geriatric nutritional risk index (GNRI) is a tool, increasingly utilized to assess the degree of malnutrition, particularly in elderly patients. Therefore, the present study attempted to validate whether GNRI could predict the risk of SSI in patients following pancreaticoduodenectomy (PD). A cohort study was retrospectively conducted on 106 patients in the Department of Digestive Surgery, Kawaguchi Municipal Medical Center, Japan from January 2007 to December 2017. All patients were subjected to nutritional screening using GNRI and followed up for the occurrence of postoperative complications, including SSI post PD. Additionally, risk factors for developing SSI, and the patient's height, body mass index and preoperative laboratory values were documented. Patients were divided into SSI (n=15) and non-SSI (n=91) groups with a determined incidence of 14.2% (15/106) for SSI. The results revealed that the SSI group had GNRI values that were significantly reduced compared with the non-SSI group (P<0.001). Receiver operating characteristic curve analysis was performed to determine the cut-off value of GNRI that conferred an increased risk of SSI; it was determined as 94 (sensitivity 80.0%, specificity 83.5%). Univariate analysis confirmed that a GNRI <94 was significantly associated with SSI (P<0.001), whereas multivariate logistic regression analysis revealed that a GNRI <94 was independently associated with SSI following PD (relative risk=1.73, 95% confidence interval=1.23-2.43; P<0.001). Therefore, a GNRI <94 is a potential predictive marker for SSI risk following PD.]]></description><identifier>ISSN: 2049-9450</identifier><identifier>EISSN: 2049-9469</identifier><identifier>DOI: 10.3892/mco.2018.1671</identifier><identifier>PMID: 30155249</identifier><language>eng</language><publisher>England: Spandidos Publications</publisher><subject>Abdomen ; Age ; Alcohol ; Body mass index ; Cancer ; Complications and side effects ; Diabetes ; Elderly ; Fistula ; Food and nutrition ; Geriatrics ; Health aspects ; Hospitals ; Infections ; Medical records ; Multivariate analysis ; Nutrition ; Oncology ; Pancreaticoduodenectomy ; Patients ; Risk factors ; Studies ; Surgical site infections ; Surgical wound infections ; Tumors</subject><ispartof>Molecular and clinical oncology, 2018-09, Vol.9 (3), p.274-278</ispartof><rights>COPYRIGHT 2018 Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2018</rights><rights>Copyright © 2018, Spandidos Publications 2018</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c373t-e99f217db6386eb5ba59b7d3a030041b8f93e5394cc78c4185c8b1dd884be62a3</citedby><cites>FETCH-LOGICAL-c373t-e99f217db6386eb5ba59b7d3a030041b8f93e5394cc78c4185c8b1dd884be62a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109673/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109673/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30155249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Funamizu, Naotake</creatorcontrib><creatorcontrib>Nakabayashi, Yukio</creatorcontrib><creatorcontrib>Iida, Tomonori</creatorcontrib><creatorcontrib>Kurihara, Kazunao</creatorcontrib><title>Geriatric nutritional risk index predicts surgical site infection after pancreaticoduodenectomy</title><title>Molecular and clinical oncology</title><addtitle>Mol Clin Oncol</addtitle><description><![CDATA[Surgical site infections (SSIs) are a well-known potential complication of surgery. They are assocaited with preoperative malnutrition and lead to increased medical costs and longer hospital stays. Therefore, surgeons should appropriately identify patients who are at a high risk. The geriatric nutritional risk index (GNRI) is a tool, increasingly utilized to assess the degree of malnutrition, particularly in elderly patients. Therefore, the present study attempted to validate whether GNRI could predict the risk of SSI in patients following pancreaticoduodenectomy (PD). A cohort study was retrospectively conducted on 106 patients in the Department of Digestive Surgery, Kawaguchi Municipal Medical Center, Japan from January 2007 to December 2017. All patients were subjected to nutritional screening using GNRI and followed up for the occurrence of postoperative complications, including SSI post PD. Additionally, risk factors for developing SSI, and the patient's height, body mass index and preoperative laboratory values were documented. Patients were divided into SSI (n=15) and non-SSI (n=91) groups with a determined incidence of 14.2% (15/106) for SSI. The results revealed that the SSI group had GNRI values that were significantly reduced compared with the non-SSI group (P<0.001). Receiver operating characteristic curve analysis was performed to determine the cut-off value of GNRI that conferred an increased risk of SSI; it was determined as 94 (sensitivity 80.0%, specificity 83.5%). Univariate analysis confirmed that a GNRI <94 was significantly associated with SSI (P<0.001), whereas multivariate logistic regression analysis revealed that a GNRI <94 was independently associated with SSI following PD (relative risk=1.73, 95% confidence interval=1.23-2.43; P<0.001). Therefore, a GNRI <94 is a potential predictive marker for SSI risk following PD.]]></description><subject>Abdomen</subject><subject>Age</subject><subject>Alcohol</subject><subject>Body mass index</subject><subject>Cancer</subject><subject>Complications and side effects</subject><subject>Diabetes</subject><subject>Elderly</subject><subject>Fistula</subject><subject>Food and nutrition</subject><subject>Geriatrics</subject><subject>Health aspects</subject><subject>Hospitals</subject><subject>Infections</subject><subject>Medical records</subject><subject>Multivariate analysis</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Pancreaticoduodenectomy</subject><subject>Patients</subject><subject>Risk factors</subject><subject>Studies</subject><subject>Surgical site infections</subject><subject>Surgical wound infections</subject><subject>Tumors</subject><issn>2049-9450</issn><issn>2049-9469</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkc1r3DAQxUVJSJYkx1yLoZdcvNWHZUuXwrIkaWChl-QsZGm8VWpbW0kO2f8-MpsuTQRiBO_Hm9E8hK4JXjIh6ffB-CXFRCxJ3ZAvaEFxJUtZ1fLk-Ob4HF3F-IzzkQ2mXJ6hc4YJ57SSC6TuITidgjPFOOWSnB91XwQX_xRutPBa7AJYZ1Is4hS2zmQxugRZ7MDMdKG7BKHY6dEE0MkZbydvYcyqH_aX6LTTfYSr93qBnu5uH9c_y82v-4f1alMa1rBUgpQdJY1tayZqaHmruWwbyzRmGFekFZ1kwJmsjGmEqYjgRrTEWiGqFmqq2QX6cfDdTe0A1sCYgu7VLrhBh73y2qmPyuh-q61_UTXBsm5YNrh5Nwj-7wQxqcFFA32vR_BTVDRjnBNc4Yx--4Q--ynktR0oKhjO90htdQ8qr8vnvmY2VSvOGRWYsblteaBM8DEG6I4jE6zmjFXOWM0ZqznjzH_9_59H-l-i7A0EuKOL</recordid><startdate>20180901</startdate><enddate>20180901</enddate><creator>Funamizu, Naotake</creator><creator>Nakabayashi, Yukio</creator><creator>Iida, Tomonori</creator><creator>Kurihara, Kazunao</creator><general>Spandidos Publications</general><general>Spandidos Publications UK Ltd</general><general>D.A. Spandidos</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180901</creationdate><title>Geriatric nutritional risk index predicts surgical site infection after pancreaticoduodenectomy</title><author>Funamizu, Naotake ; Nakabayashi, Yukio ; Iida, Tomonori ; Kurihara, Kazunao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c373t-e99f217db6386eb5ba59b7d3a030041b8f93e5394cc78c4185c8b1dd884be62a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Abdomen</topic><topic>Age</topic><topic>Alcohol</topic><topic>Body mass index</topic><topic>Cancer</topic><topic>Complications and side effects</topic><topic>Diabetes</topic><topic>Elderly</topic><topic>Fistula</topic><topic>Food and nutrition</topic><topic>Geriatrics</topic><topic>Health aspects</topic><topic>Hospitals</topic><topic>Infections</topic><topic>Medical records</topic><topic>Multivariate analysis</topic><topic>Nutrition</topic><topic>Oncology</topic><topic>Pancreaticoduodenectomy</topic><topic>Patients</topic><topic>Risk factors</topic><topic>Studies</topic><topic>Surgical site infections</topic><topic>Surgical wound infections</topic><topic>Tumors</topic><toplevel>online_resources</toplevel><creatorcontrib>Funamizu, Naotake</creatorcontrib><creatorcontrib>Nakabayashi, Yukio</creatorcontrib><creatorcontrib>Iida, Tomonori</creatorcontrib><creatorcontrib>Kurihara, Kazunao</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Molecular and clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Funamizu, Naotake</au><au>Nakabayashi, Yukio</au><au>Iida, Tomonori</au><au>Kurihara, Kazunao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Geriatric nutritional risk index predicts surgical site infection after pancreaticoduodenectomy</atitle><jtitle>Molecular and clinical oncology</jtitle><addtitle>Mol Clin Oncol</addtitle><date>2018-09-01</date><risdate>2018</risdate><volume>9</volume><issue>3</issue><spage>274</spage><epage>278</epage><pages>274-278</pages><issn>2049-9450</issn><eissn>2049-9469</eissn><abstract><![CDATA[Surgical site infections (SSIs) are a well-known potential complication of surgery. They are assocaited with preoperative malnutrition and lead to increased medical costs and longer hospital stays. Therefore, surgeons should appropriately identify patients who are at a high risk. The geriatric nutritional risk index (GNRI) is a tool, increasingly utilized to assess the degree of malnutrition, particularly in elderly patients. Therefore, the present study attempted to validate whether GNRI could predict the risk of SSI in patients following pancreaticoduodenectomy (PD). A cohort study was retrospectively conducted on 106 patients in the Department of Digestive Surgery, Kawaguchi Municipal Medical Center, Japan from January 2007 to December 2017. All patients were subjected to nutritional screening using GNRI and followed up for the occurrence of postoperative complications, including SSI post PD. Additionally, risk factors for developing SSI, and the patient's height, body mass index and preoperative laboratory values were documented. Patients were divided into SSI (n=15) and non-SSI (n=91) groups with a determined incidence of 14.2% (15/106) for SSI. The results revealed that the SSI group had GNRI values that were significantly reduced compared with the non-SSI group (P<0.001). Receiver operating characteristic curve analysis was performed to determine the cut-off value of GNRI that conferred an increased risk of SSI; it was determined as 94 (sensitivity 80.0%, specificity 83.5%). Univariate analysis confirmed that a GNRI <94 was significantly associated with SSI (P<0.001), whereas multivariate logistic regression analysis revealed that a GNRI <94 was independently associated with SSI following PD (relative risk=1.73, 95% confidence interval=1.23-2.43; P<0.001). Therefore, a GNRI <94 is a potential predictive marker for SSI risk following PD.]]></abstract><cop>England</cop><pub>Spandidos Publications</pub><pmid>30155249</pmid><doi>10.3892/mco.2018.1671</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | Spandidos Publications Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Abdomen Age Alcohol Body mass index Cancer Complications and side effects Diabetes Elderly Fistula Food and nutrition Geriatrics Health aspects Hospitals Infections Medical records Multivariate analysis Nutrition Oncology Pancreaticoduodenectomy Patients Risk factors Studies Surgical site infections Surgical wound infections Tumors |
| title | Geriatric nutritional risk index predicts surgical site infection after pancreaticoduodenectomy |
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