(Poly)cationic λ3‐Iodane‐Mediated Oxidative Ring Expansion of Secondary Alcohols

Herein, a simplified approach to the synthesis of medium‐ring ethers through the electrophilic activation of secondary alcohols with (poly)cationic λ3‐iodanes (N‐HVIs) is reported. Excellent levels of selectivity are achieved for C–O bond migration over established α‐elimination pathways, enabled by...

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Veröffentlicht in:	European journal of organic chemistry 2018-03, Vol.2018 (12), p.1460-1464
Hauptverfasser:	Walters, Jennifer C., Tierno, Anthony F., Dubin, Aimee H., Wengryniuk, Sarah E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetals Alcohol Alcohols Cations Chemical synthesis Complexity Cyclic ethers Ethers Hypervalent iodine Medium‐ring compounds Nucleophiles Ring expansion
Online-Zugang:	Volltext
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