Xingnaojing Injection Protects against Cerebral Ischemia Reperfusion Injury via PI3K/Akt-Mediated eNOS Phosphorylation

Xingnaojing (XNJ) injection, derived from traditional Chinese medicine formulation, has a protective effect against stroke, but the underlying mechanism is unclear, which severely limited its clinical application. This research aims to elucidate the role and mechanism of XNJ in reducing cerebral isc...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2018-01, Vol.2018 (2018), p.1-13
Hauptverfasser:	Zhang, Si-xi, Gao, Huan, Tao, Lina, Zhai, Jing-Hui, Qu, Xiaoyu, Zhang, Yueming, Song, Yan-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Apoptosis Brain Brain injury Cerebral ischemia Endothelial cells Endothelium Flow cytometry Herbal medicine Immunofluorescence Injection Ischemia Kinases Microvasculature Nitric oxide Phosphorylation Preconditioning Reperfusion Rodents Staining Traditional Chinese medicine Veins & arteries
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