A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery

Cell penetrating peptides (CPPs) offer great potential to deliver therapeutic molecules to previously inaccessible intracellular targets. However, many CPPs are inefficient and often leave their attached cargo stranded in the cell’s endosome. We report a versatile platform for the isolation of pepti...

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Veröffentlicht in:Scientific reports 2018-08, Vol.8 (1), p.12538-16, Article 12538
Hauptverfasser: Hoffmann, Katrin, Milech, Nadia, Juraja, Suzy M., Cunningham, Paula T., Stone, Shane R., Francis, Richard W., Anastasas, Mark, Hall, Clinton M., Heinrich, Tatjana, Bogdawa, Heique M., Winslow, Scott, Scobie, Marie N., Dewhurst, Robert E., Florez, Laura, Ong, Ferrer, Kerfoot, Maria, Champain, Danie, Adams, Abbie M., Fletcher, Susan, Viola, Helena M., Hool, Livia C., Connor, Theresa, Longville, Brooke A. C., Tan, Yew-Foon, Kroeger, Karen, Morath, Volker, Weiss, Gregory A., Skerra, Arne, Hopkins, Richard M., Watt, Paul M.
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Sprache:eng
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