Inflammatory caspase-related pyroptosis: mechanism, regulation and therapeutic potential for inflammatory bowel disease

As an essential part of programmed cell death, pyroptosis is an inflammatory response that is elicited upon infection by intracellular pathogens. Metabolic diseases, atherosclerosis and vital organ damage occur if pyroptosis is over-activated. Macrophages are the main cells that induce pyroptosis wi...

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Veröffentlicht in:Gastroenterology report 2018-08, Vol.6 (3), p.167-176
Hauptverfasser: Yuan, Yuan-Yuan, Xie, Ke-Xin, Wang, Sha-Long, Yuan, Lian-Wen
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Sprache:eng
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