Prevention of apoptotic onset rescues from glomerular tubular disconnection and podocyte loss in proteinuric kidney disease
There is a great need for treatment that arrests progression of chronic kidney disease. Increased albumin in primary urine leads to apoptosis and fibrosis of podocytes and tubular cells and is a major cause of functional deterioration. There have been many attempts to target fibrosis but few to targ...
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Veröffentlicht in: | Kidney international 2016-05, Vol.90 (1), p.135-148 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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