Prevention of apoptotic onset rescues from glomerular tubular disconnection and podocyte loss in proteinuric kidney disease

There is a great need for treatment that arrests progression of chronic kidney disease. Increased albumin in primary urine leads to apoptosis and fibrosis of podocytes and tubular cells and is a major cause of functional deterioration. There have been many attempts to target fibrosis but few to targ...

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Veröffentlicht in:Kidney international 2016-05, Vol.90 (1), p.135-148
Hauptverfasser: Burlaka, Ievgeniia, Nilsson, Linnéa M, Scott, Lena, Holtbäck, Ulla, Eklöf, Ann-Christine, Fogo, Agnes B, Brismar, Hjalmar, Aperia, Anita
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Sprache:eng
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