Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis

Approximately 20-25% of traumatic brain injury (TBI) subjects develop acute lung injury (ALI), but the pathomechanisms of TBI-induced ALI remain poorly defined. Our previous work has shown that the inflammasome plays a critical role in TBI-induced secondary pathophysiology and that inflammasome prot...

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Veröffentlicht in:	Journal of neurotrauma 2018-09, Vol.35 (17), p.2067-2076
Hauptverfasser:	Kerr, Nadine A, de Rivero Vaccari, Juan Pablo, Abbassi, Sam, Kaur, Harmanpreet, Zambrano, Ronald, Wu, Shu, Dietrich, W Dalton, Keane, Robert W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive transfer Apoptosis Biophysics Caspase Cortex Cytokines Etiology Heparin Inflammasomes Inflammation Laboratory animals Lungs Medicine Molecular weight Monoclonal antibodies Mortality Original Pediatrics Physiology Proteins Public health Surgery Trauma Traumatic brain injury
Online-Zugang:	Volltext
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