Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature
Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation...
Gespeichert in:
| Veröffentlicht in: | Annals of hematology 2018-09, Vol.97 (9), p.1627-1632 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1632 |
|---|---|
| container_issue | 9 |
| container_start_page | 1627 |
| container_title | Annals of hematology |
| container_volume | 97 |
| creator | Timmers, Nyanza K. L. M. de Maar, Josanne S. van Kruijsdijk, Rob C. M. Klein, Saskia K. |
| description | Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation of CLL should be considered in patients with any neurological symptom, irrespectively of the stage and systemic activity of CLL. |
| doi_str_mv | 10.1007/s00277-018-3329-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097746</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2032796004</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-f1d3c77907e4958a5f00ee16be4bf69db4bf64bdd8dea7daa6054148c80ea8023</originalsourceid><addsrcrecordid>eNp1kc9u1DAQxiMEokvhAbggS1w4NDB2vLFzQapWFJAqcYGz5diTrktiL7azVZ6BlyZp2vJHwpexND9_42--onhJ4S0FEO8SABOiBCrLqmJNyR4VG8orVsJW8sfFBpqqKbfzOSmepXQNQJnk7GlxwhoBQlRyU_zcoc9R98RjPIYxkTSljAPpg9G9Szq74EnoiNnH4J0h_TQc9sFMebnj-F3j4PQZsZhMdId7Ot8EcsQ4EetSdt5kYnTCRLS3RJOIR4c3t9weSe8yRp3HiM-LJ53uE764q6fFt4sPX3efyssvHz_vzi9LwwXksqO2MkI0IJA3W6m3HQAirVvkbVc3tl0Kb62VFrWwWtew5ZRLIwG1BFadFu9X3cPYDmjNugF1iG7QcVJBO_V3x7u9ugpHVUMjBK9ngTd3AjH8GDFlNbhksO-1x3mHikHFRFMD8Bl9_Q96HcboZ3u3VAUSGpgpulImhpQidg-foaCWqNUatZqjVkvUanHx6k8XDy_us50BtgJpbvkrjL9H_1_1F5OquJ8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2032308090</pqid></control><display><type>article</type><title>Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature</title><source>Springer Nature - Complete Springer Journals</source><creator>Timmers, Nyanza K. L. M. ; de Maar, Josanne S. ; van Kruijsdijk, Rob C. M. ; Klein, Saskia K.</creator><creatorcontrib>Timmers, Nyanza K. L. M. ; de Maar, Josanne S. ; van Kruijsdijk, Rob C. M. ; Klein, Saskia K.</creatorcontrib><description>Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation of CLL should be considered in patients with any neurological symptom, irrespectively of the stage and systemic activity of CLL.</description><identifier>ISSN: 0939-5555</identifier><identifier>EISSN: 1432-0584</identifier><identifier>DOI: 10.1007/s00277-018-3329-2</identifier><identifier>PMID: 29707738</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Hematology ; Leukemia ; Localization ; Medicine ; Medicine & Public Health ; Nervous system ; Oncology ; Original ; Original Article</subject><ispartof>Annals of hematology, 2018-09, Vol.97 (9), p.1627-1632</ispartof><rights>The Author(s) 2018</rights><rights>Annals of Hematology is a copyright of Springer, (2018). All Rights Reserved. © 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-f1d3c77907e4958a5f00ee16be4bf69db4bf64bdd8dea7daa6054148c80ea8023</citedby><cites>FETCH-LOGICAL-c470t-f1d3c77907e4958a5f00ee16be4bf69db4bf64bdd8dea7daa6054148c80ea8023</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00277-018-3329-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00277-018-3329-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29707738$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Timmers, Nyanza K. L. M.</creatorcontrib><creatorcontrib>de Maar, Josanne S.</creatorcontrib><creatorcontrib>van Kruijsdijk, Rob C. M.</creatorcontrib><creatorcontrib>Klein, Saskia K.</creatorcontrib><title>Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature</title><title>Annals of hematology</title><addtitle>Ann Hematol</addtitle><addtitle>Ann Hematol</addtitle><description>Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation of CLL should be considered in patients with any neurological symptom, irrespectively of the stage and systemic activity of CLL.</description><subject>Hematology</subject><subject>Leukemia</subject><subject>Localization</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nervous system</subject><subject>Oncology</subject><subject>Original</subject><subject>Original Article</subject><issn>0939-5555</issn><issn>1432-0584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kc9u1DAQxiMEokvhAbggS1w4NDB2vLFzQapWFJAqcYGz5diTrktiL7azVZ6BlyZp2vJHwpexND9_42--onhJ4S0FEO8SABOiBCrLqmJNyR4VG8orVsJW8sfFBpqqKbfzOSmepXQNQJnk7GlxwhoBQlRyU_zcoc9R98RjPIYxkTSljAPpg9G9Szq74EnoiNnH4J0h_TQc9sFMebnj-F3j4PQZsZhMdId7Ot8EcsQ4EetSdt5kYnTCRLS3RJOIR4c3t9weSe8yRp3HiM-LJ53uE764q6fFt4sPX3efyssvHz_vzi9LwwXksqO2MkI0IJA3W6m3HQAirVvkbVc3tl0Kb62VFrWwWtew5ZRLIwG1BFadFu9X3cPYDmjNugF1iG7QcVJBO_V3x7u9ugpHVUMjBK9ngTd3AjH8GDFlNbhksO-1x3mHikHFRFMD8Bl9_Q96HcboZ3u3VAUSGpgpulImhpQidg-foaCWqNUatZqjVkvUanHx6k8XDy_us50BtgJpbvkrjL9H_1_1F5OquJ8</recordid><startdate>20180901</startdate><enddate>20180901</enddate><creator>Timmers, Nyanza K. L. M.</creator><creator>de Maar, Josanne S.</creator><creator>van Kruijsdijk, Rob C. M.</creator><creator>Klein, Saskia K.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180901</creationdate><title>Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature</title><author>Timmers, Nyanza K. L. M. ; de Maar, Josanne S. ; van Kruijsdijk, Rob C. M. ; Klein, Saskia K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-f1d3c77907e4958a5f00ee16be4bf69db4bf64bdd8dea7daa6054148c80ea8023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Hematology</topic><topic>Leukemia</topic><topic>Localization</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nervous system</topic><topic>Oncology</topic><topic>Original</topic><topic>Original Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Timmers, Nyanza K. L. M.</creatorcontrib><creatorcontrib>de Maar, Josanne S.</creatorcontrib><creatorcontrib>van Kruijsdijk, Rob C. M.</creatorcontrib><creatorcontrib>Klein, Saskia K.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Timmers, Nyanza K. L. M.</au><au>de Maar, Josanne S.</au><au>van Kruijsdijk, Rob C. M.</au><au>Klein, Saskia K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature</atitle><jtitle>Annals of hematology</jtitle><stitle>Ann Hematol</stitle><addtitle>Ann Hematol</addtitle><date>2018-09-01</date><risdate>2018</risdate><volume>97</volume><issue>9</issue><spage>1627</spage><epage>1632</epage><pages>1627-1632</pages><issn>0939-5555</issn><eissn>1432-0584</eissn><abstract>Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation of CLL should be considered in patients with any neurological symptom, irrespectively of the stage and systemic activity of CLL.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29707738</pmid><doi>10.1007/s00277-018-3329-2</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0939-5555 |
| ispartof | Annals of hematology, 2018-09, Vol.97 (9), p.1627-1632 |
| issn | 0939-5555 1432-0584 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097746 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Hematology Leukemia Localization Medicine Medicine & Public Health Nervous system Oncology Original Original Article |
| title | Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T13%3A35%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Central%20nervous%20system%20localisation%20of%20chronic%20lymphocytic%20leukaemia,%20description%20of%20two%20very%20distinct%20cases%20and%20a%20review%20of%20the%20literature&rft.jtitle=Annals%20of%20hematology&rft.au=Timmers,%20Nyanza%20K.%20L.%20M.&rft.date=2018-09-01&rft.volume=97&rft.issue=9&rft.spage=1627&rft.epage=1632&rft.pages=1627-1632&rft.issn=0939-5555&rft.eissn=1432-0584&rft_id=info:doi/10.1007/s00277-018-3329-2&rft_dat=%3Cproquest_pubme%3E2032796004%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2032308090&rft_id=info:pmid/29707738&rfr_iscdi=true |