Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location
HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intr...
Gespeichert in:
Veröffentlicht in: | Otology & neurotology 2018-09, Vol.39 (8), p.e654-e659 |
---|---|
Hauptverfasser: | , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | e659 |
---|---|
container_issue | 8 |
container_start_page | e654 |
container_title | Otology & neurotology |
container_volume | 39 |
creator | Koka, Kanthaiah Riggs, William Jason Dwyer, Robert Holder, Jourdan Taylor Noble, Jack H Dawant, Benoit M Ortmann, Amanda Valenzuela, Carla V Mattingly, Jameson K Harris, Michael M O’Connell, Brendan P Litvak, Leonid M Adunka, Oliver F Buchman, Craig Alan Labadie, Robert F |
description | HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array.
BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation.
METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing.
RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789).
CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation. |
doi_str_mv | 10.1097/MAO.0000000000001906 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097527</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2089284550</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</originalsourceid><addsrcrecordid>eNpdkUtv3CAUhVHVKkkn-QdVxbIbJzwHs6kUTR61NFUiJVkjDHiGljFTsBPl3wfn3bABxHfO5d4DwDeMDjGS4uj38cUherewRPNPYA9zKirGEf_8eMaVwETugq85_ymMoFzsgF2KMKaciz0wNv2QdLWIZh2cTvA0ODOkaB7vcZX0dn0PT8bk-xWcoIlpNtug--GFtQ42fXZp8LGHTYaXyVlvBn_rYOzgme91gFdGh6JcRqMnbB986XTI7uB5n4Gbs9Prxa9qeXHeLI6XlWGc8qo1rRU1ktJgLK0gNbVEUIO5tYSwuZGdFXNBLBMYO8Fx6zpLamsZozUyLaUz8PPJdzu2G2eNm5oNapv8Rqd7FbVX_7_0fq1W8VbNy4R5qTUDP54NUvw3ujyojc_GhdK_i2NWBNWS1IxzVFD2hJoUc06uey2DkZoSUyUx9TGxIvv-_ouvopeI3nzvYhhcyn_DeOeSKkmEYV38SrxMkoogXCZVXKvJmdMH5KWi7g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2089284550</pqid></control><display><type>article</type><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</creator><creatorcontrib>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</creatorcontrib><description>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array.
BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation.
METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing.
RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789).
CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</description><identifier>ISSN: 1531-7129</identifier><identifier>EISSN: 1537-4505</identifier><identifier>DOI: 10.1097/MAO.0000000000001906</identifier><identifier>PMID: 30113557</identifier><language>eng</language><publisher>United States: Copyright by Otology & Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</publisher><subject>Adult ; Audiometry, Evoked Response - methods ; Cochlea - surgery ; Cochlear Implantation - methods ; Cochlear Implants ; Female ; Humans ; Intraoperative Neurophysiological Monitoring - methods ; Male</subject><ispartof>Otology & neurotology, 2018-09, Vol.39 (8), p.e654-e659</ispartof><rights>Copyright © 2018 by Otology & Neurotology, Inc. Image copyright © 2010 Wolters Kluwer Health/Anatomical Chart Company</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</citedby><cites>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30113557$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Koka, Kanthaiah</creatorcontrib><creatorcontrib>Riggs, William Jason</creatorcontrib><creatorcontrib>Dwyer, Robert</creatorcontrib><creatorcontrib>Holder, Jourdan Taylor</creatorcontrib><creatorcontrib>Noble, Jack H</creatorcontrib><creatorcontrib>Dawant, Benoit M</creatorcontrib><creatorcontrib>Ortmann, Amanda</creatorcontrib><creatorcontrib>Valenzuela, Carla V</creatorcontrib><creatorcontrib>Mattingly, Jameson K</creatorcontrib><creatorcontrib>Harris, Michael M</creatorcontrib><creatorcontrib>O’Connell, Brendan P</creatorcontrib><creatorcontrib>Litvak, Leonid M</creatorcontrib><creatorcontrib>Adunka, Oliver F</creatorcontrib><creatorcontrib>Buchman, Craig Alan</creatorcontrib><creatorcontrib>Labadie, Robert F</creatorcontrib><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><title>Otology & neurotology</title><addtitle>Otol Neurotol</addtitle><description>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array.
BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation.
METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing.
RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789).
CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</description><subject>Adult</subject><subject>Audiometry, Evoked Response - methods</subject><subject>Cochlea - surgery</subject><subject>Cochlear Implantation - methods</subject><subject>Cochlear Implants</subject><subject>Female</subject><subject>Humans</subject><subject>Intraoperative Neurophysiological Monitoring - methods</subject><subject>Male</subject><issn>1531-7129</issn><issn>1537-4505</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUtv3CAUhVHVKkkn-QdVxbIbJzwHs6kUTR61NFUiJVkjDHiGljFTsBPl3wfn3bABxHfO5d4DwDeMDjGS4uj38cUherewRPNPYA9zKirGEf_8eMaVwETugq85_ymMoFzsgF2KMKaciz0wNv2QdLWIZh2cTvA0ODOkaB7vcZX0dn0PT8bk-xWcoIlpNtug--GFtQ42fXZp8LGHTYaXyVlvBn_rYOzgme91gFdGh6JcRqMnbB986XTI7uB5n4Gbs9Prxa9qeXHeLI6XlWGc8qo1rRU1ktJgLK0gNbVEUIO5tYSwuZGdFXNBLBMYO8Fx6zpLamsZozUyLaUz8PPJdzu2G2eNm5oNapv8Rqd7FbVX_7_0fq1W8VbNy4R5qTUDP54NUvw3ujyojc_GhdK_i2NWBNWS1IxzVFD2hJoUc06uey2DkZoSUyUx9TGxIvv-_ouvopeI3nzvYhhcyn_DeOeSKkmEYV38SrxMkoogXCZVXKvJmdMH5KWi7g</recordid><startdate>201809</startdate><enddate>201809</enddate><creator>Koka, Kanthaiah</creator><creator>Riggs, William Jason</creator><creator>Dwyer, Robert</creator><creator>Holder, Jourdan Taylor</creator><creator>Noble, Jack H</creator><creator>Dawant, Benoit M</creator><creator>Ortmann, Amanda</creator><creator>Valenzuela, Carla V</creator><creator>Mattingly, Jameson K</creator><creator>Harris, Michael M</creator><creator>O’Connell, Brendan P</creator><creator>Litvak, Leonid M</creator><creator>Adunka, Oliver F</creator><creator>Buchman, Craig Alan</creator><creator>Labadie, Robert F</creator><general>Copyright by Otology & Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201809</creationdate><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><author>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Audiometry, Evoked Response - methods</topic><topic>Cochlea - surgery</topic><topic>Cochlear Implantation - methods</topic><topic>Cochlear Implants</topic><topic>Female</topic><topic>Humans</topic><topic>Intraoperative Neurophysiological Monitoring - methods</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koka, Kanthaiah</creatorcontrib><creatorcontrib>Riggs, William Jason</creatorcontrib><creatorcontrib>Dwyer, Robert</creatorcontrib><creatorcontrib>Holder, Jourdan Taylor</creatorcontrib><creatorcontrib>Noble, Jack H</creatorcontrib><creatorcontrib>Dawant, Benoit M</creatorcontrib><creatorcontrib>Ortmann, Amanda</creatorcontrib><creatorcontrib>Valenzuela, Carla V</creatorcontrib><creatorcontrib>Mattingly, Jameson K</creatorcontrib><creatorcontrib>Harris, Michael M</creatorcontrib><creatorcontrib>O’Connell, Brendan P</creatorcontrib><creatorcontrib>Litvak, Leonid M</creatorcontrib><creatorcontrib>Adunka, Oliver F</creatorcontrib><creatorcontrib>Buchman, Craig Alan</creatorcontrib><creatorcontrib>Labadie, Robert F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Otology & neurotology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koka, Kanthaiah</au><au>Riggs, William Jason</au><au>Dwyer, Robert</au><au>Holder, Jourdan Taylor</au><au>Noble, Jack H</au><au>Dawant, Benoit M</au><au>Ortmann, Amanda</au><au>Valenzuela, Carla V</au><au>Mattingly, Jameson K</au><au>Harris, Michael M</au><au>O’Connell, Brendan P</au><au>Litvak, Leonid M</au><au>Adunka, Oliver F</au><au>Buchman, Craig Alan</au><au>Labadie, Robert F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</atitle><jtitle>Otology & neurotology</jtitle><addtitle>Otol Neurotol</addtitle><date>2018-09</date><risdate>2018</risdate><volume>39</volume><issue>8</issue><spage>e654</spage><epage>e659</epage><pages>e654-e659</pages><issn>1531-7129</issn><eissn>1537-4505</eissn><abstract>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array.
BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation.
METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing.
RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789).
CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</abstract><cop>United States</cop><pub>Copyright by Otology & Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</pub><pmid>30113557</pmid><doi>10.1097/MAO.0000000000001906</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1531-7129 |
ispartof | Otology & neurotology, 2018-09, Vol.39 (8), p.e654-e659 |
issn | 1531-7129 1537-4505 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097527 |
source | MEDLINE; Journals@Ovid Complete |
subjects | Adult Audiometry, Evoked Response - methods Cochlea - surgery Cochlear Implantation - methods Cochlear Implants Female Humans Intraoperative Neurophysiological Monitoring - methods Male |
title | Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T16%3A49%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Intra-Cochlear%20Electrocochleography%20During%20Cochear%20Implant%20Electrode%20Insertion%20Is%20Predictive%20of%20Final%20Scalar%20Location&rft.jtitle=Otology%20&%20neurotology&rft.au=Koka,%20Kanthaiah&rft.date=2018-09&rft.volume=39&rft.issue=8&rft.spage=e654&rft.epage=e659&rft.pages=e654-e659&rft.issn=1531-7129&rft.eissn=1537-4505&rft_id=info:doi/10.1097/MAO.0000000000001906&rft_dat=%3Cproquest_pubme%3E2089284550%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2089284550&rft_id=info:pmid/30113557&rfr_iscdi=true |