Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location

HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Otology & neurotology 2018-09, Vol.39 (8), p.e654-e659
Hauptverfasser: Koka, Kanthaiah, Riggs, William Jason, Dwyer, Robert, Holder, Jourdan Taylor, Noble, Jack H, Dawant, Benoit M, Ortmann, Amanda, Valenzuela, Carla V, Mattingly, Jameson K, Harris, Michael M, O’Connell, Brendan P, Litvak, Leonid M, Adunka, Oliver F, Buchman, Craig Alan, Labadie, Robert F
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page e659
container_issue 8
container_start_page e654
container_title Otology & neurotology
container_volume 39
creator Koka, Kanthaiah
Riggs, William Jason
Dwyer, Robert
Holder, Jourdan Taylor
Noble, Jack H
Dawant, Benoit M
Ortmann, Amanda
Valenzuela, Carla V
Mattingly, Jameson K
Harris, Michael M
O’Connell, Brendan P
Litvak, Leonid M
Adunka, Oliver F
Buchman, Craig Alan
Labadie, Robert F
description HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation. METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing. RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789). CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.
doi_str_mv 10.1097/MAO.0000000000001906
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097527</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2089284550</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</originalsourceid><addsrcrecordid>eNpdkUtv3CAUhVHVKkkn-QdVxbIbJzwHs6kUTR61NFUiJVkjDHiGljFTsBPl3wfn3bABxHfO5d4DwDeMDjGS4uj38cUherewRPNPYA9zKirGEf_8eMaVwETugq85_ymMoFzsgF2KMKaciz0wNv2QdLWIZh2cTvA0ODOkaB7vcZX0dn0PT8bk-xWcoIlpNtug--GFtQ42fXZp8LGHTYaXyVlvBn_rYOzgme91gFdGh6JcRqMnbB986XTI7uB5n4Gbs9Prxa9qeXHeLI6XlWGc8qo1rRU1ktJgLK0gNbVEUIO5tYSwuZGdFXNBLBMYO8Fx6zpLamsZozUyLaUz8PPJdzu2G2eNm5oNapv8Rqd7FbVX_7_0fq1W8VbNy4R5qTUDP54NUvw3ujyojc_GhdK_i2NWBNWS1IxzVFD2hJoUc06uey2DkZoSUyUx9TGxIvv-_ouvopeI3nzvYhhcyn_DeOeSKkmEYV38SrxMkoogXCZVXKvJmdMH5KWi7g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2089284550</pqid></control><display><type>article</type><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</creator><creatorcontrib>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</creatorcontrib><description>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation. METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing. RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789). CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</description><identifier>ISSN: 1531-7129</identifier><identifier>EISSN: 1537-4505</identifier><identifier>DOI: 10.1097/MAO.0000000000001906</identifier><identifier>PMID: 30113557</identifier><language>eng</language><publisher>United States: Copyright by Otology &amp; Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</publisher><subject>Adult ; Audiometry, Evoked Response - methods ; Cochlea - surgery ; Cochlear Implantation - methods ; Cochlear Implants ; Female ; Humans ; Intraoperative Neurophysiological Monitoring - methods ; Male</subject><ispartof>Otology &amp; neurotology, 2018-09, Vol.39 (8), p.e654-e659</ispartof><rights>Copyright © 2018 by Otology &amp; Neurotology, Inc. Image copyright © 2010 Wolters Kluwer Health/Anatomical Chart Company</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</citedby><cites>FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30113557$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Koka, Kanthaiah</creatorcontrib><creatorcontrib>Riggs, William Jason</creatorcontrib><creatorcontrib>Dwyer, Robert</creatorcontrib><creatorcontrib>Holder, Jourdan Taylor</creatorcontrib><creatorcontrib>Noble, Jack H</creatorcontrib><creatorcontrib>Dawant, Benoit M</creatorcontrib><creatorcontrib>Ortmann, Amanda</creatorcontrib><creatorcontrib>Valenzuela, Carla V</creatorcontrib><creatorcontrib>Mattingly, Jameson K</creatorcontrib><creatorcontrib>Harris, Michael M</creatorcontrib><creatorcontrib>O’Connell, Brendan P</creatorcontrib><creatorcontrib>Litvak, Leonid M</creatorcontrib><creatorcontrib>Adunka, Oliver F</creatorcontrib><creatorcontrib>Buchman, Craig Alan</creatorcontrib><creatorcontrib>Labadie, Robert F</creatorcontrib><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><title>Otology &amp; neurotology</title><addtitle>Otol Neurotol</addtitle><description>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation. METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing. RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789). CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</description><subject>Adult</subject><subject>Audiometry, Evoked Response - methods</subject><subject>Cochlea - surgery</subject><subject>Cochlear Implantation - methods</subject><subject>Cochlear Implants</subject><subject>Female</subject><subject>Humans</subject><subject>Intraoperative Neurophysiological Monitoring - methods</subject><subject>Male</subject><issn>1531-7129</issn><issn>1537-4505</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUtv3CAUhVHVKkkn-QdVxbIbJzwHs6kUTR61NFUiJVkjDHiGljFTsBPl3wfn3bABxHfO5d4DwDeMDjGS4uj38cUherewRPNPYA9zKirGEf_8eMaVwETugq85_ymMoFzsgF2KMKaciz0wNv2QdLWIZh2cTvA0ODOkaB7vcZX0dn0PT8bk-xWcoIlpNtug--GFtQ42fXZp8LGHTYaXyVlvBn_rYOzgme91gFdGh6JcRqMnbB986XTI7uB5n4Gbs9Prxa9qeXHeLI6XlWGc8qo1rRU1ktJgLK0gNbVEUIO5tYSwuZGdFXNBLBMYO8Fx6zpLamsZozUyLaUz8PPJdzu2G2eNm5oNapv8Rqd7FbVX_7_0fq1W8VbNy4R5qTUDP54NUvw3ujyojc_GhdK_i2NWBNWS1IxzVFD2hJoUc06uey2DkZoSUyUx9TGxIvv-_ouvopeI3nzvYhhcyn_DeOeSKkmEYV38SrxMkoogXCZVXKvJmdMH5KWi7g</recordid><startdate>201809</startdate><enddate>201809</enddate><creator>Koka, Kanthaiah</creator><creator>Riggs, William Jason</creator><creator>Dwyer, Robert</creator><creator>Holder, Jourdan Taylor</creator><creator>Noble, Jack H</creator><creator>Dawant, Benoit M</creator><creator>Ortmann, Amanda</creator><creator>Valenzuela, Carla V</creator><creator>Mattingly, Jameson K</creator><creator>Harris, Michael M</creator><creator>O’Connell, Brendan P</creator><creator>Litvak, Leonid M</creator><creator>Adunka, Oliver F</creator><creator>Buchman, Craig Alan</creator><creator>Labadie, Robert F</creator><general>Copyright by Otology &amp; Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201809</creationdate><title>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</title><author>Koka, Kanthaiah ; Riggs, William Jason ; Dwyer, Robert ; Holder, Jourdan Taylor ; Noble, Jack H ; Dawant, Benoit M ; Ortmann, Amanda ; Valenzuela, Carla V ; Mattingly, Jameson K ; Harris, Michael M ; O’Connell, Brendan P ; Litvak, Leonid M ; Adunka, Oliver F ; Buchman, Craig Alan ; Labadie, Robert F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4535-bcbd78099c119d7283d273c15dd2246c9fd7672d4711e751befd28dd44380cb33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Audiometry, Evoked Response - methods</topic><topic>Cochlea - surgery</topic><topic>Cochlear Implantation - methods</topic><topic>Cochlear Implants</topic><topic>Female</topic><topic>Humans</topic><topic>Intraoperative Neurophysiological Monitoring - methods</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koka, Kanthaiah</creatorcontrib><creatorcontrib>Riggs, William Jason</creatorcontrib><creatorcontrib>Dwyer, Robert</creatorcontrib><creatorcontrib>Holder, Jourdan Taylor</creatorcontrib><creatorcontrib>Noble, Jack H</creatorcontrib><creatorcontrib>Dawant, Benoit M</creatorcontrib><creatorcontrib>Ortmann, Amanda</creatorcontrib><creatorcontrib>Valenzuela, Carla V</creatorcontrib><creatorcontrib>Mattingly, Jameson K</creatorcontrib><creatorcontrib>Harris, Michael M</creatorcontrib><creatorcontrib>O’Connell, Brendan P</creatorcontrib><creatorcontrib>Litvak, Leonid M</creatorcontrib><creatorcontrib>Adunka, Oliver F</creatorcontrib><creatorcontrib>Buchman, Craig Alan</creatorcontrib><creatorcontrib>Labadie, Robert F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Otology &amp; neurotology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koka, Kanthaiah</au><au>Riggs, William Jason</au><au>Dwyer, Robert</au><au>Holder, Jourdan Taylor</au><au>Noble, Jack H</au><au>Dawant, Benoit M</au><au>Ortmann, Amanda</au><au>Valenzuela, Carla V</au><au>Mattingly, Jameson K</au><au>Harris, Michael M</au><au>O’Connell, Brendan P</au><au>Litvak, Leonid M</au><au>Adunka, Oliver F</au><au>Buchman, Craig Alan</au><au>Labadie, Robert F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location</atitle><jtitle>Otology &amp; neurotology</jtitle><addtitle>Otol Neurotol</addtitle><date>2018-09</date><risdate>2018</risdate><volume>39</volume><issue>8</issue><spage>e654</spage><epage>e659</epage><pages>e654-e659</pages><issn>1531-7129</issn><eissn>1537-4505</eissn><abstract>HYPOTHESIS:Electrocochleography (ECochG) patterns observed during cochlear implant (CI) electrode insertion may provide information about scalar location of the electrode array. BACKGROUND:Conventional CI surgery is performed without actively monitoring auditory function and potential damage to intracochlear structures. The central hypothesis of this study was that ECochG obtained directly through the CI may be used to estimate intracochlear electrode position and, ultimately, residual hearing preservation. METHODS:Intracochlear ECochG was performed on 32 patients across 3 different implant centers. During electrode insertion, a 50-ms tone burst stimulus (500 Hz) was delivered at 110 dB SPL. The ECochG response was monitored from the apical-most electrode. The amplitude and phase changes of the first harmonic were imported into an algorithm in an attempt to predict the intracochlear electrode location (scala tympani [ST], translocation from ST to scala vestibuli [SV], or interaction with basilar membrane). Anatomic electrode position was verified using postoperative computed tomography (CT) with image processing. RESULTS:CT analysis confirmed 25 electrodes with ST position and 7 electrode arrays translocating from ST into SV. The ECochG algorithm correctly estimated electrode position in 26 (82%) of 32 subjects while 6 (18%) electrodes were wrongly identified as translocated (sensitivity = 100%, specificity = 77%, positive predictive value = 54%, and a negative predictive value = 100%). Greater hearing loss was observed postoperatively in participants with translocated electrode arrays (36 ± 15 dB) when compared with isolated ST insertions (28 ± 20 dB HL). This result, however, was not significant (p = 0.789). CONCLUSION:Intracochlear ECochG may provide information about CI electrode location and hearing preservation.</abstract><cop>United States</cop><pub>Copyright by Otology &amp; Neurotology, Inc. Image copyright Wolters Kluwer Health/Anatomical Chart Company</pub><pmid>30113557</pmid><doi>10.1097/MAO.0000000000001906</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1531-7129
ispartof Otology & neurotology, 2018-09, Vol.39 (8), p.e654-e659
issn 1531-7129
1537-4505
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6097527
source MEDLINE; Journals@Ovid Complete
subjects Adult
Audiometry, Evoked Response - methods
Cochlea - surgery
Cochlear Implantation - methods
Cochlear Implants
Female
Humans
Intraoperative Neurophysiological Monitoring - methods
Male
title Intra-Cochlear Electrocochleography During Cochear Implant Electrode Insertion Is Predictive of Final Scalar Location
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T16%3A49%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Intra-Cochlear%20Electrocochleography%20During%20Cochear%20Implant%20Electrode%20Insertion%20Is%20Predictive%20of%20Final%20Scalar%20Location&rft.jtitle=Otology%20&%20neurotology&rft.au=Koka,%20Kanthaiah&rft.date=2018-09&rft.volume=39&rft.issue=8&rft.spage=e654&rft.epage=e659&rft.pages=e654-e659&rft.issn=1531-7129&rft.eissn=1537-4505&rft_id=info:doi/10.1097/MAO.0000000000001906&rft_dat=%3Cproquest_pubme%3E2089284550%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2089284550&rft_id=info:pmid/30113557&rfr_iscdi=true