Molecular profiling and comprehensive genome-wide analysis of somatic copy number alterations in gastric intramucosal neoplasias based on microsatellite status

Background We attempted to identify the molecular profiles of gastric intramucosal neoplasia (IMN; low-grade dysplasia, LGD; high-grade dysplasia, HGD; intramucosal cancer, IMC) by assessing somatic copy number alterations (SCNAs) stratified by microsatellite status (microsatellite stable, MSS; micr...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2018-09, Vol.21 (5), p.765-775
Hauptverfasser:	Sugai, Tamotsu, Eizuka, Makoto, Arakawa, Noriyuki, Osakabe, Mitsumasa, Habano, Wataru, Fujita, Yasuko, Yamamoto, Eiichiro, Yamano, Hiroo, Endoh, Masaki, Matsumoto, Takayuki, Suzuki, Hiromu
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Aged Aged, 80 and over Cancer Cancer Research Carcinogenesis Class I Phosphatidylinositol 3-Kinases - genetics Cluster Analysis Copy number DNA Copy Number Variations DNA Methylation Dysplasia Female Gastric cancer Gastric Mucosa - pathology Gastroenterology Genome-Wide Association Study Genomes Humans Male Medicine Medicine & Public Health Microsatellite Instability Microsatellite Repeats Middle Aged Mutation Oncology Original Original Article p53 Protein Phenotypes Proto-Oncogene Proteins B-raf - genetics Proto-Oncogene Proteins p21(ras) - genetics Stomach Neoplasms - genetics Stomach Neoplasms - pathology Surgical Oncology Tumor Suppressor Protein p53 - genetics Tumors
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