Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders

Abnormality of dopamine D2 receptor (D2R) function, often observed as D2R supersensitivity (D2RSS), is a commonality of schizophrenia and related psychiatric disorders in humans. Moreover, virtually all psychotherapeutic agents for schizophrenia target D2R in brain. Permanent D2RSS as a feature of a...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2018-09, Vol.366 (3), p.519-526
Hauptverfasser: Kostrzewa, Richard M., Wydra, Karolina, Filip, Malgorzata, Crawford, Cynthia A., McDougall, Sanders A., Brown, Russell W., Borroto-Escuela, Dasiel O., Fuxe, Kjell, Gainetdinov, Raul R.
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Sprache:eng
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