Genetic Polymorphisms Associated with Environmental Exposure to Polycyclic Derivatives in African Children

Background. The nonracial leukopenia may be a result of exposure to polycyclic derivatives (benzene-toluene-xylene (BTX)) and may arise from a possible change in the bone marrow microenvironment. The present study sought to evaluate the association of genetic polymorphisms in xenobiotic-metabolizing...

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Veröffentlicht in:	Disease markers 2018-01, Vol.2018 (2018), p.1-9
Hauptverfasser:	Guarda, Caroline Conceição, Aleluia, Milena Magalhães, Barbosa, Cynara Gomes, Adorno, Elisângela Vitoria, Goncalves, Marilda Souza, de Miranda, Fernando Nunes, Fiuza, Luciana Magalhães, da Paz, Silvana Souza, Carvalho, Suellen Pinheiro, Yahouédéhou, Sètondji Cocou Modeste Alexandre, Santiago, Rayra Pereira, Figueiredo, Camylla Vilas Boas, Oliveira, Rodrigo Mota, Fonseca, Cleverson Alves
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group - genetics Alleles Amplified Fragment Length Polymorphism Analysis Analysis Automation Benzene Benzene Derivatives - adverse effects Blood Bone marrow Brazil - ethnology Chemical compounds Child Children Cross-Sectional Studies Cytochrome P-450 Cytochrome P-450 CYP2E1 - genetics Derivatives Environmental Exposure - adverse effects Enzymes Ethylenediaminetetraacetic acid Exposure Families & family life Family income Female Females Genetic polymorphisms Genetic research Glutathione Transferase - genetics Hematology Humans Hydrocarbons Iron Leukemia Leukocytes Leukocytes (eosinophilic) Leukopenia Leukopenia - chemically induced Leukopenia - diagnosis Leukopenia - genetics Lymphocytes Male Metabolism Monocytes Multiplex Polymerase Chain Reaction Multivariate analysis NAD(P)H Dehydrogenase (Quinone) - genetics Neutrophils Occupational health and safety Peroxidase - genetics Petroleum industry Platelets Polymerase chain reaction Polymorphism Polymorphism, Genetic Population studies Restriction fragment length polymorphism Toluene Toxicology VOCs Volatile organic compounds Xenografts Xylene
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