Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells

•Phenolic and sulfated metabolites of PCBs 3, 8, 11, and 52 were studied in vitro.•The OH-PCBs displayed toxicity to N27, SHSY-5Y, and HepG2 cells.•OH-PCBs were generally more toxic than the corresponding PCBs or PCB sulfates.•4-PCB 52 sulfate, however, showed significant toxicity to neural and hepa...

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Veröffentlicht in:Environmental toxicology and pharmacology 2018-09, Vol.62, p.69-78
Hauptverfasser: Rodriguez, Eric A., Vanle, Brigitte C., Doorn, Jonathan A., Lehmler, Hans-Joachim, Robertson, Larry W., Duffel, Michael W.
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Sprache:eng
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