Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients

Correlates of protection (CoPs) against the highly contagious respiratory disease whooping cough, caused by Bordetella pertussis , remain elusive. Characterizing the antibody response to this pathogen is essential towards identifying potential CoPs. Here, we evaluate levels, avidity and functionalit...

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Veröffentlicht in:	Scientific reports 2018-08, Vol.8 (1), p.12039-11, Article 12039
Hauptverfasser:	Hovingh, Elise S., Kuipers, Betsy, Bonačić Marinović, Axel A, Jan Hamstra, Hendrik, Hijdra, Danielle, Mughini Gras, Lapo, van Twillert, Inonge, Jongerius, Ilse, van Els, Cecile A. C. M., Pinelli, Elena
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/31 631/250/2499 631/250/255/1318 Antibody response Antigens Avidity Bordetella pertussis Cough Hemagglutinins Humanities and Social Sciences Immunoglobulin G Immunoglobulins Leukocytes (neutrophilic) multidisciplinary Opsonophagocytosis Pertussis Pertussis toxin Respiratory diseases Science Science (multidisciplinary) Toxins Vaccines Whooping cough
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