Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis

BackgroundWarm needle acupuncture (WNA) is commonly used in primary osteoporosis (OP) management in China. The evidence of its effectiveness needs to be systematically reviewed.ObjectiveThe aim of the meta-analysis was to evaluate whether using WNA alone or combined with conventional medicine benefi...

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Veröffentlicht in:Acupuncture in medicine : journal of the British Medical Acupuncture Society 2018-08, Vol.36 (4), p.215-221
Hauptverfasser: Luo, Ding, Liu, Yue, Wu, Yanan, Ma, Rui, Wang, Lin, Gu, Ronghe, Fu, Wenbin
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container_title Acupuncture in medicine : journal of the British Medical Acupuncture Society
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creator Luo, Ding
Liu, Yue
Wu, Yanan
Ma, Rui
Wang, Lin
Gu, Ronghe
Fu, Wenbin
description BackgroundWarm needle acupuncture (WNA) is commonly used in primary osteoporosis (OP) management in China. The evidence of its effectiveness needs to be systematically reviewed.ObjectiveThe aim of the meta-analysis was to evaluate whether using WNA alone or combined with conventional medicine benefits primary OP.MethodsPubMed, Embase, the Cochrane Central Register, Medline, China National Knowledge Infrastructure, Wanfang and VIP databases were searched from their inception through 30 June 2016. RCTs applying WNA independently or as an adjunct to conventional medicine, compared with conventional medicine alone, were included. Primary outcomes were bone mineral density (BMD) of the lumbar vertebrae, femoral neck, Ward’s triangle and greater trochanter. The secondary outcome was chronic pain measured by VAS score. Meta-analysis was conducted using RevMan V.5.3 software.ResultsNine RCTs involving 572 participants were included. When WNA was used as an adjunct to conventional medicine, meta-analysis revealed a statistical difference in favour of increasing BMD of the lumbar vertebrae (mean difference (MD)=0.06, 95% CI 0.03 to 0.08, P
doi_str_mv 10.1136/acupmed-2016-011227
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The evidence of its effectiveness needs to be systematically reviewed.ObjectiveThe aim of the meta-analysis was to evaluate whether using WNA alone or combined with conventional medicine benefits primary OP.MethodsPubMed, Embase, the Cochrane Central Register, Medline, China National Knowledge Infrastructure, Wanfang and VIP databases were searched from their inception through 30 June 2016. RCTs applying WNA independently or as an adjunct to conventional medicine, compared with conventional medicine alone, were included. Primary outcomes were bone mineral density (BMD) of the lumbar vertebrae, femoral neck, Ward’s triangle and greater trochanter. The secondary outcome was chronic pain measured by VAS score. Meta-analysis was conducted using RevMan V.5.3 software.ResultsNine RCTs involving 572 participants were included. When WNA was used as an adjunct to conventional medicine, meta-analysis revealed a statistical difference in favour of increasing BMD of the lumbar vertebrae (mean difference (MD)=0.06, 95% CI 0.03 to 0.08, P&lt;0.001). WNA increased BMD of the femoral neck (MD 0.14, 95% CI 0.08 to 0.21, P&lt;0.001) and greater trochanter (MD 0.09, 95% CI 0.04 to 0.15, P&lt;0.001) when used alone, and additionally decreased VAS scores (MD=−1.10, 95% CI −1.14 to −1.06, P&lt;0.001) when used as an adjunct to conventional medicine. However, the safety of WNA was not specifically reported.ConclusionsWNA may have beneficial effects on BMD and VAS scores of patients with primary OP. However, all included trials were at high risk of bias and of low quality. Further rigorous studies are needed to determine the effectiveness of WNA for primary OP treatment.</description><identifier>ISSN: 0964-5284</identifier><identifier>EISSN: 1759-9873</identifier><identifier>DOI: 10.1136/acupmed-2016-011227</identifier><identifier>PMID: 29986901</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Acupuncture ; Acupuncture Therapy - instrumentation ; Acupuncture Therapy - methods ; Age ; Bias ; Bone Density ; Fractures ; Health care ; Herbal medicine ; Humans ; Medicine ; Meta-analysis ; Needles ; Original Paper ; Osteoporosis ; Osteoporosis - physiopathology ; Osteoporosis - therapy ; Pain ; Randomized Controlled Trials as Topic ; Vertebrae</subject><ispartof>Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2018-08, Vol.36 (4), p.215-221</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2018 British Medical Acupuncutre Society</rights><rights>2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b513t-418d011d912250b23d6c00c41663ff8bb485b351138fecdd92741d740cbdf5953</citedby><cites>FETCH-LOGICAL-b513t-418d011d912250b23d6c00c41663ff8bb485b351138fecdd92741d740cbdf5953</cites><orcidid>0000-0001-5265-9200</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1136/acupmed-2016-011227$$EPDF$$P50$$Gsage$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1136/acupmed-2016-011227$$EHTML$$P50$$Gsage$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29986901$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Luo, Ding</creatorcontrib><creatorcontrib>Liu, Yue</creatorcontrib><creatorcontrib>Wu, Yanan</creatorcontrib><creatorcontrib>Ma, Rui</creatorcontrib><creatorcontrib>Wang, Lin</creatorcontrib><creatorcontrib>Gu, Ronghe</creatorcontrib><creatorcontrib>Fu, Wenbin</creatorcontrib><title>Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis</title><title>Acupuncture in medicine : journal of the British Medical Acupuncture Society</title><addtitle>Acupunct Med</addtitle><description>BackgroundWarm needle acupuncture (WNA) is commonly used in primary osteoporosis (OP) management in China. The evidence of its effectiveness needs to be systematically reviewed.ObjectiveThe aim of the meta-analysis was to evaluate whether using WNA alone or combined with conventional medicine benefits primary OP.MethodsPubMed, Embase, the Cochrane Central Register, Medline, China National Knowledge Infrastructure, Wanfang and VIP databases were searched from their inception through 30 June 2016. RCTs applying WNA independently or as an adjunct to conventional medicine, compared with conventional medicine alone, were included. Primary outcomes were bone mineral density (BMD) of the lumbar vertebrae, femoral neck, Ward’s triangle and greater trochanter. The secondary outcome was chronic pain measured by VAS score. Meta-analysis was conducted using RevMan V.5.3 software.ResultsNine RCTs involving 572 participants were included. When WNA was used as an adjunct to conventional medicine, meta-analysis revealed a statistical difference in favour of increasing BMD of the lumbar vertebrae (mean difference (MD)=0.06, 95% CI 0.03 to 0.08, P&lt;0.001). WNA increased BMD of the femoral neck (MD 0.14, 95% CI 0.08 to 0.21, P&lt;0.001) and greater trochanter (MD 0.09, 95% CI 0.04 to 0.15, P&lt;0.001) when used alone, and additionally decreased VAS scores (MD=−1.10, 95% CI −1.14 to −1.06, P&lt;0.001) when used as an adjunct to conventional medicine. However, the safety of WNA was not specifically reported.ConclusionsWNA may have beneficial effects on BMD and VAS scores of patients with primary OP. However, all included trials were at high risk of bias and of low quality. Further rigorous studies are needed to determine the effectiveness of WNA for primary OP treatment.</description><subject>Acupuncture</subject><subject>Acupuncture Therapy - instrumentation</subject><subject>Acupuncture Therapy - methods</subject><subject>Age</subject><subject>Bias</subject><subject>Bone Density</subject><subject>Fractures</subject><subject>Health care</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Medicine</subject><subject>Meta-analysis</subject><subject>Needles</subject><subject>Original Paper</subject><subject>Osteoporosis</subject><subject>Osteoporosis - physiopathology</subject><subject>Osteoporosis - therapy</subject><subject>Pain</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Vertebrae</subject><issn>0964-5284</issn><issn>1759-9873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>AFRWT</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkUuLFDEUhYMoTtv6CwQJuHFT482zEhfCMMyoMOBGcRlSSWqsplJpk6qR_vemqXZ8LMRNssh3Tu65B6HnBM4JYfK1dcs-Bt9QILIBQihtH6ANaYVutGrZQ7QBLXkjqOJn6EkpOwBQreCP0RnVWkkNZIPsF5sjnkLwY8BHx2Vy85IDHia8z0O0-YBTmUPap5zKUHC0k70NMUzzG2xxOdS3aOfB4RzuhvAd28njGGbbVG48VMVT9Ki3YwnPTvcWfb6--nT5vrn5-O7D5cVN0wnC5oYT5WsIr2sOAR1lXjoAx4mUrO9V13ElOiZqctUH572mLSe-5eA63wst2Ba9XX33S1fX4uqE2Y7mFMIkO5g_X6bhq7lNd0aC0hSgGrw6GeT0bQllNnEoLoyjnUJaiqEgW6UZZ7qiL_9Cd2nJNXClBBWSMVmPLWIr5erqSg79_TAEzLFCc6rQHCs0a4VV9eL3HPean51VAFag1CJ-ffxvz_NV0sXdfw3xAzjCuM4</recordid><startdate>20180801</startdate><enddate>20180801</enddate><creator>Luo, Ding</creator><creator>Liu, Yue</creator><creator>Wu, Yanan</creator><creator>Ma, Rui</creator><creator>Wang, Lin</creator><creator>Gu, Ronghe</creator><creator>Fu, Wenbin</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>AFRWT</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>EHMNL</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5265-9200</orcidid></search><sort><creationdate>20180801</creationdate><title>Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis</title><author>Luo, Ding ; 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Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Acupuncture in medicine : journal of the British Medical Acupuncture Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luo, Ding</au><au>Liu, Yue</au><au>Wu, Yanan</au><au>Ma, Rui</au><au>Wang, Lin</au><au>Gu, Ronghe</au><au>Fu, Wenbin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis</atitle><jtitle>Acupuncture in medicine : journal of the British Medical Acupuncture Society</jtitle><addtitle>Acupunct Med</addtitle><date>2018-08-01</date><risdate>2018</risdate><volume>36</volume><issue>4</issue><spage>215</spage><epage>221</epage><pages>215-221</pages><issn>0964-5284</issn><eissn>1759-9873</eissn><abstract>BackgroundWarm needle acupuncture (WNA) is commonly used in primary osteoporosis (OP) management in China. The evidence of its effectiveness needs to be systematically reviewed.ObjectiveThe aim of the meta-analysis was to evaluate whether using WNA alone or combined with conventional medicine benefits primary OP.MethodsPubMed, Embase, the Cochrane Central Register, Medline, China National Knowledge Infrastructure, Wanfang and VIP databases were searched from their inception through 30 June 2016. RCTs applying WNA independently or as an adjunct to conventional medicine, compared with conventional medicine alone, were included. Primary outcomes were bone mineral density (BMD) of the lumbar vertebrae, femoral neck, Ward’s triangle and greater trochanter. The secondary outcome was chronic pain measured by VAS score. Meta-analysis was conducted using RevMan V.5.3 software.ResultsNine RCTs involving 572 participants were included. When WNA was used as an adjunct to conventional medicine, meta-analysis revealed a statistical difference in favour of increasing BMD of the lumbar vertebrae (mean difference (MD)=0.06, 95% CI 0.03 to 0.08, P&lt;0.001). WNA increased BMD of the femoral neck (MD 0.14, 95% CI 0.08 to 0.21, P&lt;0.001) and greater trochanter (MD 0.09, 95% CI 0.04 to 0.15, P&lt;0.001) when used alone, and additionally decreased VAS scores (MD=−1.10, 95% CI −1.14 to −1.06, P&lt;0.001) when used as an adjunct to conventional medicine. However, the safety of WNA was not specifically reported.ConclusionsWNA may have beneficial effects on BMD and VAS scores of patients with primary OP. However, all included trials were at high risk of bias and of low quality. Further rigorous studies are needed to determine the effectiveness of WNA for primary OP treatment.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>29986901</pmid><doi>10.1136/acupmed-2016-011227</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-5265-9200</orcidid><oa>free_for_read</oa></addata></record>
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subjects Acupuncture
Acupuncture Therapy - instrumentation
Acupuncture Therapy - methods
Age
Bias
Bone Density
Fractures
Health care
Herbal medicine
Humans
Medicine
Meta-analysis
Needles
Original Paper
Osteoporosis
Osteoporosis - physiopathology
Osteoporosis - therapy
Pain
Randomized Controlled Trials as Topic
Vertebrae
title Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis
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