Clinical Pharmacokinetics in Kidney Disease: Application to Rational Design of Dosing Regimens

A change in pharmacokinetics can alter drug exposure and predispose the patient to either over- or underdosing, potentially resulting in adverse drug reactions or therapeutic failure. Kidney disease is characterized by multiple physiologic effects, which induce clinically significant changes in phar...

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Veröffentlicht in:Clinical journal of the American Society of Nephrology 2018-08, Vol.13 (8), p.1254-1263
Hauptverfasser: Roberts, Darren M, Sevastos, Jacob, Carland, Jane E, Stocker, Sophie L, Lea-Henry, Tom N
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Sprache:eng
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