Gunn rats with glial activation in the hippocampus show prolonged immobility time in the forced swimming test and tail suspension test

Introduction Recent studies imply that glial activation plays a role in the pathogenesis of psychiatric disorders, such as schizophrenia and major depression. We previously demonstrated that Gunn rats with hyperbilirubinemia show congenital gliosis and schizophrenia‐like behavior. Methods As it has...

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Veröffentlicht in:	Brain and behavior 2018-08, Vol.8 (8), p.e01028-n/a
Hauptverfasser:	Arauchi, Ryosuke, Hashioka, Sadayuki, Tsuchie, Keiko, Miyaoka, Tsuyoshi, Tsumori, Toshiko, Limoa, Erlyn, Azis, Ilhamuddin A., Oh‐Nishi, Arata, Miura, Shoko, Otsuki, Koji, Kanayama, Misako, Izuhara, Muneto, Nagahama, Michiharu, Kawano, Kiminori, Araki, Tomoko, Liaury, Kristian, Abdullah, Rostia A., Wake, Rei, Hayashida, Maiko, Inoue, Ken, Horiguchi, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocytes Astrocytes - physiology Depressive Disorder, Major - metabolism Depressive Disorder, Major - physiopathology Disease Models, Animal forced swimming test Gliosis - metabolism Gunn rat Hindlimb Suspension - methods hippocampus Hippocampus - physiology Immunohistochemistry Male Mental depression microglia Microglia - physiology Original Research Rats Rats, Gunn Rats, Wistar Rodents Schizophrenia Schizophrenia - metabolism Schizophrenia - physiopathology tail suspension test
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