Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5′ mismatches

Despite the DNA duplex being central to biological functions, many intricacies of this molecule, including the dynamic nature of mismatched base pairing, are still unknown. The unique conformations adopted by DNA mismatches can provide insight into the forces at play between nucleotides. Moreover, D...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta crystallographica. Section D, Biological crystallography. Biological crystallography., 2018-08, Vol.74 (8), p.760-768
Hauptverfasser:	Fairlamb, Max S., Whitaker, Amy M., Freudenthal, Bret D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine APE1 apurinic/apyrimidinic endonuclease 1 apurinic/apyrimidinic sites Base Pair Mismatch Base Pairing Base pairs base‐excision repair Binding Sites Compression Crystal structure Crystallography Crystallography, X-Ray Deoxyribonucleic acid DNA DNA - chemistry DNA - metabolism DNA-(Apurinic or Apyrimidinic Site) Lyase - chemistry DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism Endonuclease Guanine Hoogsteen base pairing Humans Hydrogen bonding mismatched base pairing Nuclease Nucleic Acid Conformation Nucleotides Protein Binding Proteins Research Papers Rotation Substrate Specificity Substrates X‐ray crystallography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!