Activity of gallic acid and its ester derivatives in Caenorhabditis elegans and zebrafish (Danio rerio) models

Gallic acid and its ester derivatives have shown antifungal activity in vitro. This study was performed to investigate their activity against Candida albicans and their toxicity in the animal models Caenorhabditis elegans and zebrafish embryos. The compounds protected worms from C. albicans infectio...

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Veröffentlicht in:	Future medicinal chemistry 2017-10, Vol.9 (16), p.1863-1872
Hauptverfasser:	Singulani, Junya de Lacorte, Scorzoni, Liliana, Gomes, Paulo César, Nazaré, Ana Carolina, Polaquini, Carlos Roberto, Regasini, Luis Octávio, Fusco-Almeida, Ana Marisa, Mendes-Giannini, Maria José Soares
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - chemistry Amphotericin B - pharmacology Animals Antifungal Agents - chemistry Antifungal Agents - pharmacology Caenorhabditis elegans - drug effects Candida albicans - drug effects Esters - chemistry Esters - pharmacology Gallic Acid - analogs & derivatives Gallic Acid - chemistry Gallic Acid - pharmacology Humans Molecular Structure Short Communication Structure-Activity Relationship Zebrafish
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