DUSP1 induces apatinib resistance by activating the MAPK pathway in gastric cancer

Dual‑specificity phosphatase‑1 (DUSP1) is an oncogene that is associated with cancer progression following drug resistance. In order to investigate the potential relationship between DUSP1 and apatinib resistance in gastric cancer cells, we preformed many assays to study this problem. DUSP1 gene was...

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Veröffentlicht in:	Oncology reports 2018-09, Vol.40 (3), p.1203-1222
Hauptverfasser:	Teng, Fei, Xu, Zhiyuan, Chen, Jiahui, Zheng, Guowei, Zheng, Guodian, Lv, Hang, Wang, Yiping, Wang, Lijing, Cheng, Xiangdong
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer therapies Care and treatment Cell cycle Cell growth Chemotherapy Clinical trials Development and progression Drug resistance Enzyme regulation Experiments Gastric cancer Genetic aspects Health aspects Kinases Medical prognosis Metastasis Oncogenes Phosphatase Phosphatases Phosphorylation Prostate Proteins Stomach cancer Studies Tumors
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