Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates

Detection of acute HIV infection is critical for HIV public health and diagnostics. Clinical fourth-generation antigen (Ag)/antibody (Ab) combination (combo) and p24 Ag immunoassays have enhanced detection of acute infection compared to Ab-alone assays but require ongoing evaluation with currently c...

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Veröffentlicht in:Journal of clinical microbiology 2018-08, Vol.56 (8)
Hauptverfasser: Stone, Mars, Bainbridge, John, Sanchez, Ana M, Keating, Sheila M, Pappas, Andrea, Rountree, Wes, Todd, Chris, Bakkour, Sonia, Manak, Mark, Peel, Sheila A, Coombs, Robert W, Ramos, Eric M, Shriver, M Kathleen, Contestable, Paul, Nair, Sangeetha Vijaysri, Wilson, David H, Stengelin, Martin, Murphy, Gary, Hewlett, Indira, Denny, Thomas N, Busch, Michael P
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Sprache:eng
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