Integrating long-range connectivity information into de Bruijn graphs

Abstract Motivation The de Bruijn graph is a simple and efficient data structure that is used in many areas of sequence analysis including genome assembly, read error correction and variant calling. The data structure has a single parameter k, is straightforward to implement and is tractable for lar...

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Veröffentlicht in:	Bioinformatics 2018-08, Vol.34 (15), p.2556-2565
Hauptverfasser:	Turner, Isaac, Garimella, Kiran V, Iqbal, Zamin, McVean, Gil
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms bioinformatics Data Visualization drug resistance genes genome assembly genomics Genomics - methods graphs High-Throughput Nucleotide Sequencing - methods Humans Klebsiella pneumoniae Klebsiella pneumoniae - genetics Original Papers Sequence Analysis, DNA - methods Software
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