The effect of moderate weight loss, with or without (1, 3)(1, 6)-β-glucan addition, on subcutaneous adipose tissue inflammatory gene expression in young subjects with uncomplicated obesity

Purpose Obesity is characterized by insulin resistance and low-grade systemic and adipose tissue (AT) inflammation. It remains unclear whether beneficial effects of weight loss are related to AT inflammation. We aimed to assess the effect of weight loss during low-calorie diet on insulin sensitivity...

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Veröffentlicht in:	Endocrine 2018-08, Vol.61 (2), p.275-284
Hauptverfasser:	Strączkowski, Marek, Nikołajuk, Agnieszka, Majewski, Radosław, Filarski, Remigiusz, Stefanowicz, Magdalena, Matulewicz, Natalia, Karczewska-Kupczewska, Monika
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adult beta-Glucans - administration & dosage beta-Glucans - pharmacology Biopsy Body weight loss Caloric Restriction Diabetes Endocrinology Female Gelatinase B Gene expression Gene Expression - drug effects Humanities and Social Sciences Humans Hypocaloric diet Immunomodulation Inflammation Inflammation - complications Inflammation - genetics Inflammation - metabolism Inflammation - pathology Insulin Insulin resistance Insulin Resistance - genetics Interleukin 1 Interleukin 18 Interleukin 6 Interleukin 6 receptors Internal Medicine Janus kinase Janus kinase 2 Male Medicine Medicine & Public Health Monocyte chemoattractant protein 1 multidisciplinary Nutrient deficiency Obesity Obesity - complications Obesity - diet therapy Obesity - genetics Obesity - pathology Original Original Article Science Stat3 protein Subcutaneous Fat - drug effects Subcutaneous Fat - metabolism Subcutaneous Fat - pathology Weight control Weight Loss - physiology Young Adult β-Glucan
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