NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione

Cadmium (Cd 2+ ) is toxic to living organisms because it causes the malfunction of essential proteins and induces oxidative stress. NADP + -dependent cytosolic isocitrate dehydrogenase (IDH) provides reducing energy to counteract oxidative stress via oxidative decarboxylation of isocitrate. Intrigui...

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