Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis

Dihydroartemisinin–piperaquine is an effective and well tolerated artemisinin-based combination therapy that has been assessed extensively for the prevention and treatment of malaria. Piperaquine, similar to several structurally related antimalarials currently used, can prolong cardiac ventricular r...

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Veröffentlicht in:	The Lancet infectious diseases 2018-08, Vol.18 (8), p.913-923
Hauptverfasser:	Chan, Xin Hui S, Win, Yan Naung, Mawer, Laura J, Tan, Jireh Y, Brugada, Josep, White, Nicholas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Antimalarials Antimalarials - administration & dosage Antimalarials - adverse effects Artemisinin Artemisinins - administration & dosage Artemisinins - adverse effects Autopsies Autopsy Bayes Theorem Bayesian analysis Cardiotoxicity Case management Cause of Death Charities Clinical trials Cohort Studies Death Dihydroartemisinin Drug dosages Drug Therapy, Combination - mortality EKG Electrocardiogram Electrocardiography Female Heart Heart rate Humans Infections Infectious diseases Malaria Malaria - drug therapy Management Medical research Medicine, Preventive Meta-analysis Mortality Mozambique Pregnancy Prevention Preventive health services Prospective Studies Quinolines - administration & dosage Quinolines - adverse effects Reviews Risk assessment Studies Systematic review Therapy Vector-borne diseases Ventricle Womens health
Online-Zugang:	Volltext
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