Overexpression of Annexin A1 protects against benzo[a]pyrene‑induced bronchial epithelium injury

The incidence of asthma is increasing worldwide. Bronchial epithelium injury is common in asthma. The regulatory role of Annexin A1 (ANXA1) in bronchial epithelium injury is currently not well understood. The aim of the present study was to evaluate the role of ANXA1 on bronchial epithelium injury....

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Veröffentlicht in:	Molecular medicine reports 2018-07, Vol.18 (1), p.349-357
Hauptverfasser:	Cui, Yanfei, Yang, Shengya
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Annexins Apoptosis Asthma B-cell lymphoma Bcl-2 protein Benzo(a)pyrene Care and treatment Caspase Caspase-3 Cyclin D1 Development and progression Enzyme-linked immunosorbent assay Epithelial cells Epithelium Flow cytometry Focal adhesion kinase Gene expression Genetic aspects Glutathione Health aspects Kinases Lung diseases Lymphocytes B Malondialdehyde Oxidative stress Phosphorylation Polymerase chain reaction PTEN protein Reactive oxygen species Roles Signal transduction Superoxide dismutase
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