Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow

Brain-derived neurotrophic factor (BDNF) is an important modulator of constitutive stress responses mediated by limbic frontotemporal circuits, and its gene contains a functional polymorphism (Val66Met) that may influence trait stress sensitivity. Reports of an association of this polymorphism with...

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Veröffentlicht in:	Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2017-03, Vol.27 (3), p.2175-2182
Hauptverfasser:	Wei, Shau-Ming, Eisenberg, Daniel P, Nabel, Katherine G, Kohn, Philip D, Kippenhan, J Shane, Dickinson, Dwight, Kolachana, Bhaskar, Berman, Karen F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anxiety - genetics Anxiety - physiopathology Brain - diagnostic imaging Brain - physiology Brain Mapping Brain-Derived Neurotrophic Factor - genetics Cerebrovascular Circulation - genetics Cerebrovascular Circulation - physiology European Continental Ancestry Group - genetics Female Heterozygote Homozygote Humans Male Middle Aged Original Personality - genetics Personality - physiology Personality Tests Polymorphism, Single Nucleotide Positron-Emission Tomography Rest Young Adult
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