Wind-up in lamina I spinoparabrachial neurons: a role for reverberatory circuits

Wind-up is a frequency-dependent increase in the response of spinal cord neurons, which is believed to underlie temporal summation of nociceptive input. However, whether spinoparabrachial neurons, which likely contribute to the affective component of pain, undergo wind-up was unknown. Here, we addre...

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Veröffentlicht in:	Pain (Amsterdam) 2018-08, Vol.159 (8), p.1484-1493
Hauptverfasser:	Hachisuka, Junichi, Omori, Yu, Chiang, Michael C., Gold, Michael S., Koerber, H. Richard, Ross, Sarah E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Interneurons - physiology Mice Neurons - physiology Pain - physiopathology Patch-Clamp Techniques Spinal Cord - physiopathology Spinal Cord Dorsal Horn - physiopathology
Online-Zugang:	Volltext
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