Low-intensity pulsed ultrasound stimulation facilitates in vitro osteogenic differentiation of human adipose-derived stem cells via up-regulation of heat shock protein (HSP)70, HSP90, and bone morphogenetic protein (BMP) signaling pathway

Low-intensity pulsed ultrasound (LIPUS) has positive effects on osteogenic differentiation. However, the effect of LIPUS on osteogenic differentiation of human adipose-derived stem cells (hASCs) is unclear. In the present study, we investigated whether LIPUS could promote the proliferation and osteo...

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Veröffentlicht in:	Bioscience reports 2018-05, Vol.38 (3)
Hauptverfasser:	Zhang, Zhonglei, Ma, Yalin, Guo, Shaowen, He, Yi, Bai, Gang, Zhang, Wenjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Adipocytes - radiation effects Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 7 - genetics Cell Differentiation - genetics Cell Differentiation - radiation effects Cell Proliferation - genetics Gene Expression Regulation, Developmental - radiation effects HSP70 Heat-Shock Proteins - genetics HSP90 Heat-Shock Proteins - genetics Humans Osteoblasts - cytology Osteoblasts - metabolism Osteoblasts - radiation effects Osteogenesis - genetics Osteogenesis - radiation effects Stem Cells - radiation effects Ultrasonic Waves
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