Microsatellite instability in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus: a retrospective study

To analyze the loss of mismatch repair (MMR) system protein expression in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus (BE). This study retrospectively analyzed the data from 70 patients with pathohistological diagnosis of BE or esophageal adenocarcinoma (EAC) treated at the Cli...

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Veröffentlicht in:	Croatian medical journal 2018-06, Vol.59 (3), p.100-107
Hauptverfasser:	Pulanic, Roland, Jakic-Razumovic, Jasminka, Brcic, Iva, Markos, Pave, Brcic, Luka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adult Aged Barrett esophagus Barrett Esophagus - metabolism Barrett Esophagus - pathology Biological markers Biomarkers, Tumor - metabolism Clinical Science DNA Mismatch Repair DNA-Binding Proteins - metabolism Esophageal Neoplasms - metabolism Esophageal Neoplasms - pathology Female Gene expression Genetic aspects Humans Immunoenzyme Techniques Male Metaplasia Microsatellite Instability Middle Aged Mismatch Repair Endonuclease PMS2 - metabolism MutL Protein Homolog 1 - metabolism MutS Homolog 2 Protein - metabolism Neoplasm Proteins - metabolism Retrospective Studies Tumor Suppressor Protein p53 - metabolism
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