Clinical Features and Diagnostic Usefulness of Antibodies to Clustered Acetylcholine Receptors in the Diagnosis of Seronegative Myasthenia Gravis

IMPORTANCE: Cell-based assays (CBAs) were shown to improve detection of acetylcholine receptor (AChR) antibodies in patients with myasthenia gravis (MG). Herein, we asked whether these assays were able to help determine the diagnosis in patients studied in routine clinical practice. OBJECTIVES: To d...

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Veröffentlicht in:	JAMA neurology 2015-06, Vol.72 (6), p.642-649
Hauptverfasser:	Rodríguez Cruz, Pedro M, Al-Hajjar, Michal, Huda, Saif, Jacobson, Leslie, Woodhall, Mark, Jayawant, Sandeep, Buckley, Camilla, Hilton-Jones, David, Beeson, David, Vincent, Angela, Leite, Maria Isabel, Palace, Jacqueline
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Autoantibodies Biological Assay - standards Child Child, Preschool Female Humans Infant Male Middle Aged Myasthenia Gravis - diagnosis Myasthenia Gravis - immunology Myasthenia Gravis - physiopathology Phenotype Receptors, Cholinergic - immunology Sensitivity and Specificity Severity of Illness Index Young Adult
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